The immunogenetics of psoriasis: a comprehensive review

JL Harden, JG Krueger, AM Bowcock - Journal of autoimmunity, 2015 - Elsevier
Psoriasis vulgaris is a common, chronic inflammatory skin disease with a complex etiology
involving genetic risk factors and environmental triggers. Here we describe the many known …

Genetic and epigenetic basis of psoriasis pathogenesis

A Chandra, A Ray, S Senapati, R Chatterjee - Molecular immunology, 2015 - Elsevier
Psoriasis is a chronic inflammatory skin disease whose prevalence varies among different
populations worldwide. It is a complex multi-factorial disease and the exact etiology is …

[HTML][HTML] Genome-wide association analysis of psoriatic arthritis and cutaneous psoriasis reveals differences in their genetic architecture

PE Stuart, RP Nair, LC Tsoi, T Tejasvi, S Das… - The American Journal of …, 2015 - cell.com
Psoriasis vulgaris (PsV) is a common inflammatory and hyperproliferative skin disease. Up
to 30% of people with PsV eventually develop psoriatic arthritis (PsA), an inflammatory …

[HTML][HTML] Enhanced meta-analysis and replication studies identify five new psoriasis susceptibility loci

LC Tsoi, SL Spain, E Ellinghaus, PE Stuart… - Nature …, 2015 - nature.com
Psoriasis is a chronic autoimmune disease with complex genetic architecture. Previous
genome-wide association studies (GWAS) and a recent meta-analysis using Immunochip …

[HTML][HTML] Genome-wide meta-analysis identifies multiple novel associations and ethnic heterogeneity of psoriasis susceptibility

X Yin, HQ Low, L Wang, Y Li, E Ellinghaus… - Nature …, 2015 - nature.com
Psoriasis is a common inflammatory skin disease with complex genetics and different
degrees of prevalence across ethnic populations. Here we present the largest trans-ethnic …

Interactions between host factors and the skin microbiome

A SanMiguel, EA Grice - Cellular and Molecular Life Sciences, 2015 - Springer
The skin is colonized by an assemblage of microorganisms which, for the most part,
peacefully coexist with their hosts. In some cases, these communities also provide vital …

[HTML][HTML] Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis

X Zuo, L Sun, X Yin, J Gao, Y Sheng, J Xu… - Nature …, 2015 - nature.com
Genome-wide association studies (GWASs) have reproducibly associated∼ 40
susceptibility loci with psoriasis. However, the missing heritability is evident and the …

[HTML][HTML] Genome-wide comparative analysis of atopic dermatitis and psoriasis gives insight into opposing genetic mechanisms

H Baurecht, M Hotze, S Brand, C Büning… - The American Journal of …, 2015 - cell.com
Atopic dermatitis and psoriasis are the two most common immune-mediated inflammatory
disorders affecting the skin. Genome-wide studies demonstrate a high degree of genetic …

Genetics of psoriasis

SK Mahil, F Capon, JN Barker - Dermatologic clinics, 2015 - derm.theclinics.com
Substantial progress has been made into identifying the genetic determinants of common
immune-mediated diseases. This has highlighted biologic pathways involved in disease …

Biomarkers of an autoimmune skin disease—psoriasis

S Jiang, TE Hinchliffe, T Wu - Genomics, Proteomics and …, 2015 - academic.oup.com
Psoriasis is one of the most prevalent autoimmune skin diseases. However, its etiology and
pathogenesis are still unclear. Over the last decade, omics-based technologies have been …