Connectomics: a new paradigm for understanding brain disease

A Fornito, ET Bullmore - European Neuropsychopharmacology, 2015 - Elsevier
In recent years, pathophysiological models of brain disorders have shifted from an emphasis
on understanding pathology in specific brain regions to characterizing disturbances of …

Toxoplasma gondii‐induced neuronal alterations

A Parlog, D Schlüter, IR Dunay - Parasite immunology, 2015 - Wiley Online Library
The zoonotic pathogen Toxoplasma gondii infects over 30% of the human population. The
intracellular parasite can persist lifelong in the CNS within neurons modifying their function …

Age‐related changes in the topological organization of the white matter structural connectome across the human lifespan

T Zhao, M Cao, H Niu, XN Zuo, A Evans… - Human brain …, 2015 - Wiley Online Library
Lifespan is a dynamic process with remarkable changes in brain structure and function.
Previous neuroimaging studies have indicated age‐related microstructural changes in …

Disrupted brain network topology in pediatric posttraumatic stress disorder: A resting‐state fMRI study

X Suo, D Lei, K Li, F Chen, F Li, L Li… - Human brain …, 2015 - Wiley Online Library
Children exposed to natural disasters are vulnerable to the development of posttraumatic
stress disorder (PTSD). Recent studies of other neuropsychiatric disorders have used graph …

Developmental changes in brain network hub connectivity in late adolescence

STE Baker, DI Lubman, M Yücel, NB Allen… - Journal of …, 2015 - Soc Neuroscience
The human brain undergoes substantial development throughout adolescence and into
early adulthood. This maturational process is thought to include the refinement of …

Imaging human brain networks to improve the clinical efficacy of non-invasive brain stimulation

MV Sale, JB Mattingley, A Zalesky, L Cocchi - … & Biobehavioral Reviews, 2015 - Elsevier
The flexible integration of segregated neural processes is essential to healthy brain function.
Advances in neuroimaging techniques have revealed that psychiatric and neurological …

Reconciling abnormalities of brain network structure and function in schizophrenia

A Fornito, ET Bullmore - Current opinion in neurobiology, 2015 - Elsevier
Highlights•Schizophrenia patients often show reduced structural connectivity.•Despite this,
increased functional connectivity is a common finding.•Structure–function decoupling may …

A selective review of structural connectivity abnormalities of schizophrenic patients at different stages of the disease

E Canu, F Agosta, M Filippi - Schizophrenia research, 2015 - Elsevier
Schizophrenia has long been hypothesized to result from a disconnection syndrome due to
a disruption of the association fibers of the brain. However, only with the advent of in vivo …

Identification of infants at high‐risk for autism spectrum disorder using multiparameter multiscale white matter connectivity networks

Y Jin, CY Wee, F Shi, KH Thung, D Ni… - Human brain …, 2015 - Wiley Online Library
Autism spectrum disorder (ASD) is a wide range of disabilities that cause life‐long cognitive
impairment and social, communication, and behavioral challenges. Early diagnosis and …

Further neuroimaging evidence for the deficit subtype of schizophrenia: a cortical connectomics analysis

AL Wheeler, M Wessa, PR Szeszko, G Foussias… - JAMA …, 2015 - jamanetwork.com
Importance The clinical heterogeneity of schizophrenia has hindered neurobiological
investigations aimed at identifying neural correlates of the disorder. Objective To identify …