Converging models of schizophrenia–Network alterations of prefrontal cortex underlying cognitive impairments
The prefrontal cortex (PFC) and its connections with other brain areas are crucial for
cognitive function. Cognitive impairments are one of the core symptoms associated with …
cognitive function. Cognitive impairments are one of the core symptoms associated with …
Electrophysiological endophenotypes in rodent models of schizophrenia and psychosis
AM Rosen, T Spellman, JA Gordon - Biological psychiatry, 2015 - Elsevier
Schizophrenia is caused by a diverse array of risk factors and results in a similarly diverse
set of symptoms. Electrophysiological endophenotypes lie between risks and symptoms and …
set of symptoms. Electrophysiological endophenotypes lie between risks and symptoms and …
The interaction between maternal immune activation and alpha 7 nicotinic acetylcholine receptor in regulating behaviors in the offspring
WL Wu, CE Adams, KE Stevens, KH Chow… - Brain, behavior, and …, 2015 - Elsevier
Mutation of human chromosome 15q13. 3 increases the risk for autism and schizophrenia.
One of the noteworthy genes in 15q13. 3 is CHRNA7, which encodes the nicotinic …
One of the noteworthy genes in 15q13. 3 is CHRNA7, which encodes the nicotinic …
Modulation of schizophrenia-related genes in the forebrain of adolescent and adult rats exposed to maternal immune activation
AM Hemmerle, R Ahlbrand, SL Bronson… - Schizophrenia …, 2015 - Elsevier
Maternal immune activation (MIA) is an environmental risk factor for schizophrenia, and may
contribute to other developmental disorders including autism and epilepsy. Activation of pro …
contribute to other developmental disorders including autism and epilepsy. Activation of pro …
ZNF804A transcriptional networks in differentiating neurons derived from induced pluripotent stem cells of human origin
J Chen, M Lin, A Hrabovsky, E Pedrosa, J Dean… - PloS one, 2015 - journals.plos.org
ZNF804A (Zinc Finger Protein 804A) has been identified as a candidate gene for
schizophrenia (SZ), autism spectrum disorders (ASD), and bipolar disorder (BD) in …
schizophrenia (SZ), autism spectrum disorders (ASD), and bipolar disorder (BD) in …
Closing the translational gap between mutant mouse models and the clinical reality of psychotic illness
CM O'Tuathaigh, JL Waddington - Neuroscience & Biobehavioral Reviews, 2015 - Elsevier
As animal models of psychotic illness become more refined, mutant mouse models have
become increasingly prominent through their ability to inform on the structural, cellular and …
become increasingly prominent through their ability to inform on the structural, cellular and …
Motor and behavioral phenotype in conditional mutants with targeted ablation of cortical D1 dopamine receptor-expressing cells
Abstract D1-dopamine receptors (Drd1a) are highly expressed in the deep layers of the
cerebral cortex and the striatum. A number of human diseases such as Huntington disease …
cerebral cortex and the striatum. A number of human diseases such as Huntington disease …