Association between variants of zinc finger genes and psychiatric disorders: systematic review and meta-analysis

Y Sun, D Hu, J Liang, YP Bao, SQ Meng, L Lu… - Schizophrenia research, 2015 - Elsevier
Psychiatric disorders have a negative impact on society and human lives. Genetic factors
are involved in the occurrence and development of psychiatric diseases. ZNF804A has been …

[HTML][HTML] Expression analysis in a rat psychosis model identifies novel candidate genes validated in a large case–control sample of schizophrenia

A Ingason, I Giegling, AM Hartmann, J Genius… - Translational …, 2015 - nature.com
Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis
in healthy individuals and exacerbate schizophrenia symptoms in patients. In this study we …

[HTML][HTML] ZNF804A transcriptional networks in differentiating neurons derived from induced pluripotent stem cells of human origin

J Chen, M Lin, A Hrabovsky, E Pedrosa, J Dean… - PloS one, 2015 - journals.plos.org
ZNF804A (Zinc Finger Protein 804A) has been identified as a candidate gene for
schizophrenia (SZ), autism spectrum disorders (ASD), and bipolar disorder (BD) in …

[HTML][HTML] Associations between the schizophrenia susceptibility gene ZNF804A and clinical outcomes in psychosis

A Wickramasinghe, AD Tulloch, RD Hayes… - Translational …, 2015 - nature.com
We sought to test the hypothesis that the rs1344706 A allele will be associated with worse
clinical outcome in first-episode psychosis. A data linkage was set up between a large …

[HTML][HTML] Genetic variants associated with susceptibility to psychosis in late-onset Alzheimer's disease families

S Barral, BN Vardarajan, D Reyes-Dumeyer… - Neurobiology of …, 2015 - Elsevier
Psychotic symptoms are frequent in late-onset Alzheimer's disease (LOAD) patients.
Although the risk for psychosis in LOAD is genetically mediated, no genes have been …

Experimental validation of candidate schizophrenia gene CALN1 as a target for microRNA-137

S Xia, X Zhou, T Wang, Q Zhang, Q Li, Y Liu, Q Xing… - Neuroscience …, 2015 - Elsevier
Abstract MIR137, which encodes microRNA-137 (miR-137), and several of its target genes
exhibit genome-wide significant associations with schizophrenia. In a previous study, we …

Replication of ZNF804A gene variant associations with risk of heroin addiction

DB Hancock, JL Levy, NC Gaddis… - Genes, Brain and …, 2015 - Wiley Online Library
Heroin addiction is heritable, but few specific genetic variants have been reproducibly
associated with this disease. The zinc finger protein 804A (ZNF804A) gene is a biologically …

[HTML][HTML] Genetics, sleep and memory: a recall-by-genotype study of ZNF804A variants and sleep neurophysiology

C Hellmich, C Durant, MW Jones, NJ Timpson… - BMC medical …, 2015 - Springer
Background Schizophrenia is a complex, polygenic disorder for which over 100 genetic
variants have been identified that correlate with diagnosis. However, the biological …

[HTML][HTML] The Rat Homolog of the Schizophrenia Susceptibility Gene ZNF804A Is Highly Expressed during Brain Development, Particularly in Growth Cones

KH Hinna, K Rich, Å Fex-Svenningsen, E Benedikz - PLoS One, 2015 - journals.plos.org
A single nucleotide polymorphism in the ZNF804A gene, rs1344706, is associated with
schizophrenia. The polymorphism has been suggested to alter fetal expression of ZNF804A …

Overlapping etiology of neurodevelopmental disorders

E Kelleher, A Corvin - The genetics of neurodevelopmental …, 2015 - Wiley Online Library
Neurodevelopmental disorders (NDDs) are relatively common but represent a wide range of
different etiologies. This chapter outlines significant overlap between entities. It includes …