Pathophysiological insights of methylglyoxal induced type-2 diabetes

S Dornadula, B Elango… - Chemical research in …, 2015 - ACS Publications
Diabetes mellitus is a metabolic disorder constituting a major health problem whose
prevalence has gradually increased worldwide over the past few decades. Type 2 diabetes …

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

MR de Oliveira, GC Ferreira, PF Schuck… - Chemico-biological …, 2015 - Elsevier
Glycation, a process that occurs endogenously and generates advanced glycation end
products (AGEs), presents an important role in cases of neurodegeneration, as for instance …

Neuroprotective effect of sulforaphane against methylglyoxal cytotoxicity

C Angeloni, M Malaguti, B Rizzo… - Chemical Research …, 2015 - ACS Publications
Glycation, an endogenous process that leads to the production of advanced glycation end
products (AGEs), plays a role in the etiopathogenesis of different neurodegenerative …

Glycation and hypoxia: two key factors for adipose tissue dysfunction

P Matafome, T Rodrigues… - Current medicinal …, 2015 - ingentaconnect.com
Many aspects of adipose tissue pathophysiology in metabolic diseases have been
described in the last years. One of such aspects is certainly hypoxia, which was shown to …

Occupational and environmental bronchiolar disorders

KJ Cummings, K Kreiss - Seminars in respiratory and critical …, 2015 - thieme-connect.com
Occupational and environmental causes of bronchiolar disorders are recognized on the
basis of case reports, case series, and, less commonly, epidemiologic investigations …

[HTML][HTML] Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin‑induced diabetic rats and its active compound emodin …

E Sohn, J Kim, CS Kim, K Jo… - Molecular Medicine …, 2015 - spandidos-publications.com
Podocyte injury contributes to renal damage and, eventually, to the occurrence of proteinuria
in diabetic nephropathy. The aim of the present study was to investigate the effect of an …

Efeitos do metilglioxal em parâmetros comportamentais e neuroquímicos in vitro e ex vivo

F Hansen - 2015 - lume.ufrgs.br
O diabetes mellitus é uma doença metabólica caracterizada por níveis elevados de glicose
no jejum e está associada com a perda da função cognitiva e um maior risco de …

[引用][C] 甲基乙二醛与糖尿病痛性神经病变的相关性研究进展

张雪利, 李全民 - 中国医药, 2015