In the last decade, the biomedical applications of nanoparticles (NPs)(eg cell tracking,
biosensing, magnetic resonance imaging (MRI), targeted drug delivery, and tissue …

MUC1 antigen is recognized as a high‐molecular‐weight glycoprotein that is unexpectedly
over‐expressed in human breast and other carcinomas. In contrast, C595 a monoclonal …

Alterations in mucin expression and glycosylation are associated with cancer development.
Underglycosylated mucin-1 (uMUC1) is overexpressed in most malignant adenocarcinomas …

Gold nanorods (AuNRs) have attracted considerable attention in plasmonic photothermal
therapy for cancer treatment by exploiting their selective and localized heating effect due to …

Understanding the effects of immune responses on targeted delivery of nanoparticles is
important for clinical translations of new cancer imaging and therapeutic nanoparticles. In …

Quantitative analysis of MUC1, a cell membrane associated mucin, expressed by intact cells
of epithelial origin previously has been limited to flow cytometry, which requires using large …

Background The use of ultrasmall superparamagnetic iron oxide (USPIO) nanoparticles to
visualize cells has been applied clinically, showing the potential for monitoring cells in vivo …

Aim: To develop biocompatible, tumor-specific multifunctional iron-oxide nanoconstructs
targeting neuroblastoma, an aggressive pediatric malignancy. Materials & methods: Clinical …

A high-performance imaging probe with NIR luminescence and synergistically enhanced
T1− T2 relaxivity was synthesized. This nanoprobe exhibits a relatively high tumor-targeting …

Abstract Chronic Myeloid Leukemia (CML) is caused by the fusion oncoprotein BCR-ABL,
whose dysregulated tyrosine kinase activity drives malignant transformation. In this thesis, I …