STUDY QUESTION Are single-nucleotide polymorphisms (SNPs) at the interleukin 1A (IL1A)
gene locus associated with endometriosis risk? SUMMARY ANSWER We found evidence …

Metabolite quantitative traits carry great promise for epidemiological studies, and their
genetic background has been addressed using Genome-Wide Association Studies (GWAS) …

NMDA receptors (NMDARs) are key mediators of glutamatergic transmission and synaptic
plasticity, and their dysregulation has been linked to diverse neuropsychiatric and …

The public health burden of alcohol is unevenly distributed across the life course, with levels
of use, abuse, and dependence increasing across adolescence and peaking in early …

Schizophrenia has been associated with a large range of autoimmune diseases, with a
history of any autoimmune disease being associated with a 45% increase in risk for the …

Objective Clinical response to antipsychotic medications can vary markedly in patients with
schizophrenia. Identifying genetic variants associated with treatment response could help …

The treatment of bipolar disorder (BD) usually requires combination therapies, with the
critical issue of the emergence of adverse drug reactions (ADRs) and the possibility of low …

BACKGROUND: The genetic basis of longevity is an important field of study because the
majority of supercentenarian cases experience healthy aging and may only show age …

Humans chronically treated with the a-typical antipsychotic Olanzapine (OLZ) often
experience weight gain and insulin resistance, and co-administration of the anticonvulsant …

Este trabajo se centra en el estudio del papel que desarrollan determinados genes
relacionados con el neurodesarrollo, tales como los polimorfismos BDNF, NRG1 y CNR1 …