Immune-mediated (IM) adverse drug reactions (ADRs) are an underrecognized source of
preventable morbidity, mortality, and cost. Increasingly, genetic variation in the HLA loci is …

Transfusion‐related acute lung injury (TRALI), a syndrome of respiratory distress caused by
blood transfusion, is the leading cause of transfusion‐related mortality. The majority of …

Abstract The Immuno Polymorphism Database (IPD) was developed to provide a centralized
system for the study of polymorphism in genes of the immune system. Through the IPD …

Despite its biological importance, tRNA has not been adequately sequenced by standard
methods because of its abundant post-transcriptional modifications and stable structure …

Genome-wide association studies of the related chronic inflammatory bowel diseases (IBD)
known as Crohn's disease and ulcerative colitis have shown strong evidence of association …

Human leukocyte antigen (HLA) genes confer substantial risk for autoimmune diseases on a
log-additive scale. Here we speculated that differences in autoantigen-binding repertoires …

Allele-level resolution data at primary HLA typing is the ideal for most histocompatibility
testing laboratories. Many high-throughput molecular HLA typing approaches are unable to …

We conducted a large-scale genetic analysis on giant cell arteritis (GCA), a polygenic
immune-mediated vasculitis. A case-control cohort, comprising 1,651 case subjects with …

The first decade of Genome Wide Association Studies (GWAS) has uncovered a wealth of
disease-associated variants. Two important derivations will be the translation of this …

Clinical mastitis (CM) is one of the health disorders with large impacts on dairy farming
profitability and animal welfare. The objective of this study was to perform a genome-wide …