Extracellular vesicle-mediated export of fungal RNA

R Peres da Silva, R Puccia, ML Rodrigues… - Scientific reports, 2015 - nature.com
Extracellular vesicles (EVs) play an important role in the biology of various organisms,
including fungi, in which they are required for the trafficking of molecules across the cell wall …

Unisexual versus bisexual mating in Cryptococcus neoformans: Consequences and biological impacts

C Fu, S Sun, RB Billmyre, KC Roach… - Fungal Genetics and …, 2015 - Elsevier
Cryptococcus neoformans is an opportunistic human fungal pathogen and can undergo both
bisexual and unisexual mating. Despite the fact that one mating type is dispensable for …

Characterization of RNA silencing components in the plant pathogenic fungus Fusarium graminearum

Y Chen, Q Gao, M Huang, Y Liu, Z Liu, X Liu, Z Ma - Scientific reports, 2015 - nature.com
The RNA interference (RNAi) plays a critical role in gene regulation in a variety of eukaryotic
organisms. However, the role of RNAi remains largely unclear in plant pathogenic fungi. In …

Genome evolution and innovation across the four major lineages of Cryptococcus gattii

RA Farrer, CA Desjardins, S Sakthikumar, S Gujja… - MBio, 2015 - Am Soc Microbiol
Cryptococcus gattii is a fungal pathogen of humans, causing pulmonary infections in
otherwise healthy hosts. To characterize genomic variation among the four major lineages of …

Mechanism of siRNA production from repetitive DNA

Q Yang, QA Ye, Y Liu - Genes & development, 2015 - genesdev.cshlp.org
RNAi is a conserved genome defense mechanism in eukaryotes that protects against
deleterious effects of transposons and viral invasion. Repetitive DNA loci are a major source …

Rising to the challenge of multiple Cryptococcus species and the diseases they cause

A Idnurm, X Lin - Fungal Genetics and Biology, 2015 - Elsevier
Cryptococcus neoformans and Cryptococcus gattii are well-studied basidiomyceteous
yeasts that are capable of causing disease in healthy and immunocompromised people. The …

RNA silencing in filamentous fungi: from basics to applications

NB Quoc, H Nakayashiki - … Transformation Systems in Fungi, Volume 2, 2015 - Springer
In the post-genomics era, RNAi has rapidly become a powerful reverse genetic tool for
elucidating gene function in a wide range of eukaryotes including fungi. In this review, we …

Targets of the Sex Inducer homeodomain proteins are required for fungal development and virulence in Cryptococcus neoformans

ME Mead, BC Stanton, EK Kruzel… - Molecular …, 2015 - Wiley Online Library
In the yeast S accharomyces cerevisiae, the regulation of cell types by homeodomain
transcription factors is a key paradigm; however, many questions remain regarding this class …

New technology and resources for cryptococcal research

N Zhang, YD Park, PR Williamson - Fungal Genetics and Biology, 2015 - Elsevier
Rapid advances in molecular biology and genome sequencing have enabled the
generation of new technology and resources for cryptococcal research. RNAi-mediated …

Qip gene in Fusarium oxysporum is required for normal hyphae morphology and virulence

L Cheng, J Ling, L Liang, Z Luo, J Zhang, B Xie - Mycology, 2015 - Taylor & Francis
Ribonucleic acid (RNA)-silencing mechanisms exist in many eukaryotes to regulate a variety
of biological processes. The known molecular components are related to Dicers, Argonautes …