Inhibitory receptor expression on CD8+ T cells is linked to functional responses against Trypanosoma cruzi antigens in chronic chagasic patients

P Lasso, J Mateus, P Pavia, F Rosas, N Roa… - The Journal of …, 2015 - journals.aai.org
In mammals, chronic diseases resulting from infectious agents have been associated with
functional T cell response deficiency, a high frequency of terminally differentiated T cells, the …

NK-, NKT-and CD8-derived IFNγ drives myeloid cell activation and erythrophagocytosis, resulting in trypanosomosis-associated acute anemia

J Cnops, C De Trez, B Stijlemans, J Keirsse… - PLoS …, 2015 - journals.plos.org
African trypanosomes are the causative agents of Human African Trypanosomosis
(HAT/Sleeping Sickness) and Animal African Trypanosomosis (AAT/Nagana). A common …

Low Frequency of Circulating CD8+ T Stem Cell Memory Cells in Chronic Chagasic Patients with Severe Forms of the Disease

J Mateus, P Lasso, P Pavia, F Rosas… - PLoS neglected …, 2015 - journals.plos.org
Background CD8+ T cells have been shown to play a crucial role in Trypanosoma cruzi
infection. Memory CD8+ T cells can be categorised based on their distinct differentiation …

Deficiency of antigen-specific B cells results in decreased Trypanosoma cruzi systemic but not mucosal immunity due to CD8 T cell exhaustion

NL Sullivan, CS Eickhoff, J Sagartz… - The Journal of …, 2015 - journals.aai.org
Vaccines against mucosally invasive, intracellular pathogens must induce a myriad of
immune responses to provide optimal mucosal and systemic protection, including CD4+ T …

[PDF][PDF] lipopolysaccharide-induced MHC class I on human dendritic cells and impairs antigen presentation to specific CD8+ T lymphocytes

L Van Overtvelt, M Andrieu, VÂ Verhasselt, F Connan… - academia.edu
Trypanosoma cruzi, the etiological agent of Chagas' disease, may persist for many years in
its mammalian host. This suggests escape from the immune response and particularly a …

[PDF][PDF] Inhibitory Receptor Expression on CD8

CJP González, A Cuéllar, N Roa, MC Thomas… - 2015 - academia.edu
In mammals, chronic diseases resulting from infectious agents have been associated with
functional T cell response deficiency, a high frequency of terminally differentiated T cells, the …

[PDF][PDF] A prolinemia como um fator de severidade na infecção causada pelo Trypanosoma cruzi.

SC Rocha - 2015 - academia.edu
Foi demonstrado que a L-prolina é fundamental para o metabolismo das formas
intracelulares de T. cruzi e está envolvida em processos de resistência a diferentes …