The non-communicable disease, cancer, is one of the major causes of death across the
world and is forecast to increase by 75% to reach close to 25 million cases over the next two …

The impairment of wound healing in diabetic patients is an important clinical problem.
Proper keratinocyte migration and proliferation are the crucial steps during …

Hypertrophic scarring/hypertrophic scars (HS) is a highly prevalent condition following burns
and trauma wounds. Numerous studies have demonstrated that transforming growth factor …

Shikonin, a naphthoquinone pigment isolated from the Chinese herbal Zicao, has been
shown to exhibit antioxidant and anticancer effects. In the present study, we investigated the …

Shikonin, a natural naphthoquinone pigment isolated from Lithospermum erythrorhizon, has
been reported to suppress growth of various cancer cells. This study was aimed to …

Background. Shikonin is a major chemical component of zicao that possesses anti‐
inflammatory properties and the ability to mediate cellular and humoral immunity, especially …

Chondrocyte apoptosis is mostly responsible for the development and progression of
osteoarthritis. IL-1β is generally served as an agent that induces chondrocyte apoptosis …

Shikonin, shikonofuran and their derivatives are the main bioactive components of Zicao, a
traditional Chinese herbal medicine prepared with the dried roots of Lithospermum …

Lithospermum erythrorhizon has long been used as a traditional oriental medicine. In this
study, the acute and 28-day subacute oral dose toxicity studies of hexane extracts of the …

Ценными биологически активными веществами Воробейника краснокорневого
являются нафтохинон шиконин и его производные. В результате проведения …