Adrenocortical tumors (ACT) in children are very rare and are most frequently diagnosed in
the context of the Li-Fraumeni syndrome, a multiple cancer syndrome linked to germline …

Tumors of the adrenal cortex can be diagnosed by the investigation of clinical signs of
steroid excess or incidentally on medical imaging. Most tumors are unilateral and can be …

Malignant gliomas represent the most devastating group of brain tumors in adults, among
which glioblastoma multiforme (GBM) exhibits the highest malignancy rate. Despite …

Introduction Plasma microRNAs (miRNAs) are promising biomarkers for many forms of
cancer in humans; however, a fundamental concern is the lack of standardization in current …

The graphene oxide (GO) modified pencil graphite electrodes (PGEs) were utilized for
electrochemical monitoring of microRNA-34a (miRNA-34a) in this study. The GO …

Several lines of evidence support the relevance of microRNAs in both adrenocortical and
adrenomedullary (pheochromocytomas) tumors. Significantly differentially expressed …

Field effect in cancer, also called “field cancerization”, attempts to explain the development
of multiple primary tumors and locally recurrent cancer. The concept of field effect in cancer …

The available drug treatment options for adrenocortical carcinoma (ACC) are limited. In our
previous studies, the in vitro activity of 9-cis retinoic acid (9-cisRA) on adrenocortical NCI …

Purpose. The interaction of hormones of the pituitary‐adrenal axis and adrenal cortex‐
associated circulating microRNAs is mostly unknown. We have studied the effects of …

Genomic diagnostics in cancer has evolved since the completion of the Human Genome
Project and the advancements made in diagnosis and therapy in chronic myelogenous …