Excessive accumulation of lipids can lead to lipotoxicity, cell dysfunction and alteration in
metabolic pathways, both in adipose tissue and peripheral organs, like liver, heart, pancreas …

Identification of subjects at increased risk for cardiovascular events plays a central role in the
worldwide efforts to improve prevention, prediction, diagnosis, and prognosis of …

Background—High-throughput profiling of circulating metabolites may improve
cardiovascular risk prediction over established risk factors. Methods and Results—We …

Abstract Aims/hypothesis South Asian individuals have an increased risk of diabetes
compared with Europeans that is unexplained by obesity and traditional or established …

With the contribution from more than one hundred CNS neurotrauma experts, this book
provides a comprehensive and up-to-date account on the latest developments in the area of …

Prediabetes represents an elevation of plasma glucose above the normal range but below
that of clinical diabetes. Prediabetes includes individuals with IFG, IGT, IFG with IGT and …

Diabetes is characterized by altered metabolism of key molecules and regulatory pathways.
The phenotypic expression of diabetes and associated complications encompasses …

Obesity and diabetes arise from an intricate interplay between both genetic and
environmental factors. It is well recognized that obesity plays an important role in the …

Ceramides and sphingolipids are a family of lipid molecules that circulate in serum and
accumulate in skeletal muscle, promoting insulin resistance. Plasma ceramide and …

Background: Human metabolism is influenced by dietary factors and lifestyle, environmental,
and genetic factors; thus, men who exclude some or all animal products from their diet might …