Towards large-scale, human-based, mesoscopic neurotechnologies

EF Chang - Neuron, 2015 - cell.com
Direct human brain recordings have transformed the scope of neuroscience in the past
decade. Progress has relied upon currently available neurophysiological approaches in the …

Epilepsy: new advances

SL Moshé, E Perucca, P Ryvlin, T Tomson - The Lancet, 2015 - thelancet.com
Epilepsy affects 65 million people worldwide and entails a major burden in seizure-related
disability, mortality, comorbidities, stigma, and costs. In the past decade, important advances …

Minimally invasive surgical approaches for temporal lobe epilepsy

EF Chang, DJ Englot, S Vadera - Epilepsy & Behavior, 2015 - Elsevier
Surgery can be a highly effective treatment for medically refractory temporal lobe epilepsy
(TLE). The emergence of minimally invasive resective and nonresective treatment options …

Development and validation of nomograms to provide individualised predictions of seizure outcomes after epilepsy surgery: a retrospective analysis

L Jehi, R Yardi, K Chagin, L Tassi, GL Russo… - The Lancet …, 2015 - thelancet.com
Background Half of patients who have resective brain surgery for drug-resistant epilepsy
have recurrent postoperative seizures. Although several single predictors of seizure …

Breathing inhibited when seizures spread to the amygdala and upon amygdala stimulation

BJ Dlouhy, BK Gehlbach, CJ Kreple… - Journal of …, 2015 - Soc Neuroscience
Sudden unexpected death in epilepsy (SUDEP) is increasingly recognized as a common
and devastating problem. Because impaired breathing is thought to play a critical role in …

The evolution of epilepsy surgery between 1991 and 2011 in nine major epilepsy centers across the United States, Germany, and Australia

L Jehi, D Friedman, C Carlson, G Cascino, S Dewar… - …, 2015 - Wiley Online Library
Objective Epilepsy surgery is the most effective treatment for select patients with drug‐
resistant epilepsy. In this article, we aim to provide an accurate understanding of the current …

Epilepsy surgery in the United States: analysis of data from the National Association of Epilepsy Centers

K Kaiboriboon, AM Malkhachroum, A Zrik, A Daif… - Epilepsy research, 2015 - Elsevier
Objective To examine trends in epilepsy-related surgical procedures performed at major
epilepsy centers in the US between 2003 and 2012, and in the service provision …

Increasing utilization of pediatric epilepsy surgery in the United States between 1997 and 2009

EM Pestana Knight, NK Schiltz, PM Bakaki… - …, 2015 - Wiley Online Library
Objective To examine national trends of pediatric epilepsy surgery usage in the United
States between 1997 and 2009. Methods We performed a serial cross‐sectional study of …

Changing profiles of pediatric epilepsy surgery candidates over time: a nationwide single‐center experience from 1990 to 2011

HJ Lamberink, K Boshuisen, PC van Rijen… - …, 2015 - Wiley Online Library
Objective Over the past decades, the number of epilepsy surgeries in children has increased
and indications for surgery have broadened. We studied the changes in patient …

Perceptions of epilepsy surgery: a systematic review and an explanatory model of decision-making

SR Dewar, HC Pieters - Epilepsy & Behavior, 2015 - Elsevier
Background Clear evidence supports the benefits of surgery over medical therapy for
patients with refractory focal epilepsy. Surgical procedures meet the needs of fewer than 2 …