The near-atomic cryoEM structure of a flexible filamentous plant virus shows homology of its coat protein with nucleoproteins of animal viruses

X Agirrezabala, E Mendez-Lopez, G Lasso… - Elife, 2015 - elifesciences.org
Flexible filamentous viruses include economically important plant pathogens. Their viral
particles contain several hundred copies of a helically arrayed coat protein (CP) protecting a …

Insight into the Ebola virus nucleocapsid assembly mechanism: crystal structure of Ebola virus nucleoprotein core domain at 1.8 Å resolution

S Dong, P Yang, G Li, B Liu, W Wang, X Liu, B Xia… - Protein & …, 2015 - academic.oup.com
Ebola virus (EBOV) is a key member of Filoviridae family and causes severe human
infectious diseases with high morbidity and mortality. As a typical negative-sense single …

Peptidyl aldehyde NK-1.8 k suppresses enterovirus 71 and enterovirus 68 infection by targeting protease 3C

Y Wang, B Yang, Y Zhai, Z Yin, Y Sun… - Antimicrobial Agents …, 2015 - Am Soc Microbiol
Enterovirus (EV) is one of the major causative agents of hand, foot, and mouth disease in the
Pacific-Asia region. In particular, EV71 causes severe central nervous system infections, and …

NADP+-Preferring d-Lactate Dehydrogenase from Sporolactobacillus inulinus

L Zhu, X Xu, L Wang, H Dong, B Yu… - Applied and …, 2015 - Am Soc Microbiol
Hydroxy acid dehydrogenases, including l-and d-lactate dehydrogenases (L-LDH and D-
LDH), are responsible for the stereospecific conversion of 2-keto acids to 2-hydroxyacids …

Structural and functional diversity of nairovirus-encoded nucleoproteins

W Wang, X Liu, X Wang, H Dong, C Ma… - Journal of …, 2015 - Am Soc Microbiol
The nairoviruses include assorted tick-borne bunyaviruses that are emerging as causative
agents of infectious diseases among humans and animals. As negative-sense single …

Biochemical characterization of recombinant enterovirus 71 3C protease with fluorogenic model peptide substrates and development of a biochemical assay

L Shang, S Zhang, X Yang, J Sun, L Li… - Antimicrobial agents …, 2015 - Am Soc Microbiol
ABSTRACT Enterovirus 71 (EV71), a primary pathogen of hand, foot, and mouth disease
(HFMD), affects primarily infants and children. Currently, there are no effective drugs against …

Structural characterization by transmission electron microscopy and immunoreactivity of recombinant Hendra virus nucleocapsid protein expressed and purified from …

LA Pearce, M Yu, LJ Waddington, JA Barr… - Protein expression and …, 2015 - Elsevier
Hendra virus (family Paramyxoviridae) is a negative sense single-stranded RNA virus
(NSRV) which has been found to cause disease in humans, horses, and experimentally in …

A comprehensive procedure for antiviral inhibitor discovery using EV71 as an example

L Cao, S Zhu, Y Wang, Z Lou, Y Sun - Biophysics Reports, 2015 - Springer
The prevalence of chronic viral infectious diseases, the emergence and re-emergence of
new viral infections, and in particular, resistance to currently used antiviral drugs have led to …