The powerful genome-wide association studies (GWAS) revealed common mutations that
increase susceptibility for schizophrenia (SZ) and bipolar disorder (BD), but the vast majority …

Schizophrenia (SCZ) is a complex and heterogeneous mental disorder that affects about 1%
of global population. In recent years, considerable progress has been made in genetic …

To understand the regulation of tissue-specific gene expression, the GTEx Consortium
generated RNA-seq expression data for more than thirty distinct human tissues. This data …

Background Whole-genome expression studies in the peripheral tissues of patients affected
by schizophrenia (SCZ) can provide new insight into the molecular basis of the disorder and …

Antagonists of the N-methyl-D-aspartate (NMDA)-type glutamate receptor induce psychosis
in healthy individuals and exacerbate schizophrenia symptoms in patients. In this study we …

Molecular chaperones monitor the proper folding of misfolded proteins and function as the
first line of defense against mutant protein aggregation in neurodegenerative diseases. The …

Limited research has assessed associations between schizophrenia and genetic variants of
the ankyrin repeat and kinase domain containing 1 (ANKK1) and lymphotoxin-alpha (LTA) …

Introduction Genetic analyses including genome‐wide association studies have reported an
intronic single nucleotide polymorphism (SNP) rs1006737 in CACNA1C gene (encoded …

Background Cognitive deficits have been identified as an important core feature of
schizophrenia. Single nucleotide polymorphisms in the transcription factor 4 (TCF4) gene …

Genome-wide association studies (GWAS) of schizophrenia have identified multiple risk
variants with robust association signals for schizophrenia. However, these variants could …