On the basis of the high and consistent expression of prostate-specific membrane antigen
(PSMA) in metastatic prostate cancer (PC), the goal of this study was the development …

Due to the propensity of relapse and resistance with prolonged androgen deprivation
therapy (ADT), there is a growing interest in developing non‐hormonal therapeutic …

The lack of specificity of traditional cytotoxic drugs has triggered the development of
anticancer agents that selectively address specific molecular targets. An intrinsic property of …

Plants are able to reiteratively form new organs in an environmentally adaptive manner
during postembryonic development. Organ formation in plants is dependent on stem cell …

The brominated flame retardants (BFRs) 1, 2-dibromo-4-(1, 2-dibromoethyl) cyclohexane
(TBECH or DBE-DCBH) and allyl 2, 4, 6-tribromophenyl ether (ATE or TBP-AE) are …

Due to its consistently high expression in especially metastatic prostate cancer (PCa), PSMA
(prostate-specific membrane antigen) represents an ideal target for both diagnostic imaging …

Cancer, group of diseases characterized by an uncontrolled cell growth, represents one of
the great challenges of modern clinical research. Currently, the standard treatment of the …

A pharmaceutical drug or medicine is a substance that has known biological effects on living
organisms with the aim of treatment, cure, prevention, or diagnosis of a disease or …

The objective of this work was to develop a novel dual-modal protein for targeted vascular
occlusion of solid tumor neovasculature mediated by in-situ polymer synthesis. Towards this …

During last three decades, a great effort was invested to the development of polymer
conjugates of low molecular drugs with the aim to improve the specific targeting of drugs to …