L Pantoni, F Fierini, A Poggesi… - Geriatrics & …, 2015 - Wiley Online Library
The evidence on the clinical significance of cerebral white matter changes (WMC) has mounted over the past few decades. WMC are recognized as one of the neuroimaging …
White matter hyperintensities (WMH) of presumed vascular origin are a common finding in brain magnetic resonance imaging of older individuals and contribute to cognitive and …
AM Tuladhar, AGW van Norden, KF de Laat… - NeuroImage: Clinical, 2015 - Elsevier
Cerebral small vessel disease, including white matter hyperintensities (WMH) and lacunes of presumed vascular origin, is common in elderly people and is related to cognitive …
AM Tuladhar, AT Reid, E Shumskaya, KF De Laat… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—White matter hyperintensities (WMH) are associated with clinically heterogeneous symptoms that cannot be explained by these lesions alone. It is …
DS Knopman, ME Griswold, ST Lirette, RF Gottesman… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The relationships between cerebrovascular lesions visible on imaging and cognition are complex. We explored the possibility that the cerebral cortical …
BN Huisa, A Caprihan, J Thompson, J Prestopnik… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—The blood–brain barrier (BBB) is disrupted in small vessel disease patients with lacunes and white matter hyperintensities (WMHs). The relationship of …
J Filomena, I Riba-Llena, E Vinyoles, JL Tovar… - …, 2015 - Am Heart Assoc
Blood pressure (BP) variability is associated with stroke risk, but less is known about subclinical cerebral small vessel disease (CSVD). We aimed to determine whether CSVD …
MR Benedictus, AC van Harten, AE Leeuwis, T Koene… - Stroke, 2015 - Am Heart Assoc
Background and Purpose—In patients with subjective cognitive decline, we assessed whether small vessel disease was associated with clinical progression and cognitive …
Background and Purpose—The term metabolic syndrome describes the clustering of risk factors found in many individuals with obesity. Because of their pathophysiology, we …