Modern temporal network theory: a colloquium

P Holme - The European Physical Journal B, 2015 - Springer
The power of any kind of network approach lies in the ability to simplify a complex system so
that one can better understand its function as a whole. Sometimes it is beneficial, however …

Cancer stem cells display extremely large evolvability: alternating plastic and rigid networks as a potential mechanism: network models, novel therapeutic target …

P Csermely, J Hódsági, T Korcsmáros, D Módos… - Seminars in cancer …, 2015 - Elsevier
Cancer is increasingly perceived as a systems-level, network phenomenon. The major trend
of malignant transformation can be described as a two-phase process, where an initial …

Evaluating the evidence for targeting FOXO3a in breast cancer: a systematic review

S Taylor, M Lam, C Pararasa, JEP Brown… - Cancer cell …, 2015 - Springer
Background Tumour cells show greater dependency on glycolysis so providing a sufficient
and rapid energy supply for fast growth. In many breast cancers, estrogen, progesterone and …

Schisandrin B suppresses glioma cell metastasis mediated by inhibition of mTOR/MMP-9 signal pathway

Y Jiang, Q Zhang, J Bao, C Du, J Wang, Q Tong… - Biomedicine & …, 2015 - Elsevier
Background Malignant glioma is the aggressive tumor in the brain and is characterized by
high morbidity, high mortality. The main purpose of the present study was to investigate the …

[HTML][HTML] MiR-142 acts as a tumor suppressor in osteosarcoma cell lines by targeting Rac1

Z Zheng, M Ding, J Ni, D Song… - Oncology …, 2015 - spandidos-publications.com
Although the 5-year survival rate of osteosarcoma (OS) has risen to~ 60-70%, a substantial
portion of patients still respond poorly to chemotherapy and have a high risk of relapse or …

Multitarget network strategies to influence memory and forgetting: the Ras/MAPK pathway as a novel option

M David Gyurko, A Steták, C Soti… - Mini Reviews in …, 2015 - ingentaconnect.com
The Ras/mitogen activated protein kinase (MAPK) pathway has key importance in
development, cell differentiation and senescence, tumorigenesis, learning and memory. The …