[HTML][HTML] HIV-associated TB syndemic: a growing clinical challenge worldwide

MT Montales, A Chaudhury, A Beebe, S Patil… - Frontiers in public …, 2015 - frontiersin.org
The association of tuberculosis (TB) with human immunodeficiency virus (HIV) infection and
acquired immune deficiency syndrome over the past several years has become an …

The role of virus infection in deregulating the cytokine response to secondary bacterial infection

D Mehta, C Petes, K Gee, S Basta - Journal of Interferon & Cytokine …, 2015 - liebertpub.com
Proinflammatory cytokines are produced by macrophages and dendritic cells (DCs) after
infection to stimulate T helper (Th) cells, linking innate and adaptive immunity. Virus …

Disulfiram and copper ions kill Mycobacterium tuberculosis in a synergistic manner

AG Dalecki, M Haeili, S Shah, A Speer… - Antimicrobial agents …, 2015 - Am Soc Microbiol
Tuberculosis is a severe disease affecting millions worldwide. Unfortunately, treatment
strategies are hampered both by the prohibitively long treatment regimen and the rise of …

[HTML][HTML] Attrition of TCR Vα7. 2+ CD161++ MAIT cells in HIV-tuberculosis co-infection is associated with elevated levels of PD-1 expression

A Saeidi, VL Tien Tien, R Al-Batran, HA Al-Darraji… - PLoS …, 2015 - journals.plos.org
Mucosal-associated invariant T (MAIT) cells are evolutionarily conserved antimicrobial MR1-
restricted CD8+ T cells co-expressing the semi-invariant TCR Vα7. 2, and are numerous in …

Design and synthesis of novel carbazole tethered pyrrole derivatives as potent inhibitors of Mycobacterium tuberculosis

G Surineni, P Yogeeswari, D Sriram… - Bioorganic & medicinal …, 2015 - Elsevier
A series of novel carbazole tethered pyrrole derivatives were designed by coupling core
fragments of antitubercular agents, carbazole and substituted pyrrole in single molecular …

[HTML][HTML] Age, sex, and nutritional status modify the CD4+ T-cell recovery rate in HIV–tuberculosis co-infected patients on combination antiretroviral therapy

AE Ezeamama, E Mupere, J Oloya, L Martinez… - International Journal of …, 2015 - Elsevier
Background Baseline age and combination antiretroviral therapy (cART) were examined as
determinants of CD4+ T-cell recovery during 6 months of tuberculosis (TB) therapy …

[HTML][HTML] Mechanistic insights on immunosenescence and chronic immune activation in HIV-tuberculosis co-infection

EM Shankar, V Velu, A Kamarulzaman… - World journal of …, 2015 - ncbi.nlm.nih.gov
Immunosenescence is marked by accelerated degradation of host immune responses
leading to the onset of opportunistic infections, where senescent T cells show remarkably …

Concurrent loss of co-stimulatory molecules and functional cytokine secretion attributes leads to proliferative senescence of CD8+ T cells in HIV/TB co-infection

A Saeidi, YK Chong, YK Yong, HY Tan, M Barathan… - Cellular …, 2015 - Elsevier
The role of T-cell immunosenescence and functional CD8+ T-cell responses in HIV/TB co-
infection is unclear. We examined and correlated surrogate markers of HIV disease …

Structural and enzymatic studies of essential enzymes in mycobacterium tuberculosis

JJ Lindenberger - 2015 - rave.ohiolink.edu
Tuberculosis (TB) continues to be a global health threat. The World Health Organization
estimates that nearly 8.6 million new TB cases were reported, and 1.3 million people …

Calidad de vida en pacientes infectados con VIH y co-infectados de VIH/TB en un hospital de segundo nivel de atención IMSS en Monterrey, NL, México

N Kiloki Kioko - 2015 - dspace.um.edu.mx
La progresión del virus de inmunodeficiencia humana (VIH) en el mundo y su interacción
con la coexistencia de tuberculosis han generado diversos estudios sobre la calidad de …