Serotonin in Parkinson's disease

M Politis, F Niccolini - Behavioural brain research, 2015 - Elsevier
Parkinson's disease is a chronic neurodegenerative disorder characterized by the motor
symptoms of bradykinesia, tremor, rigidity and postural instability. However, non-motor …

Catechol-O-Methyltransferase Inhibitors in Parkinson's Disease

T Müller - Drugs, 2015 - Springer
Inhibitors of catechol-O-methyltransferase (COMT) are commonly used as an adjunct to
levodopa in patients with Parkinson's disease (PD) for the amelioration of wearing-off …

[HTML][HTML] Parkinson's disease and its management: part 1: disease entity, risk factors, pathophysiology, clinical presentation, and diagnosis

G DeMaagd, A Philip - Pharmacy and therapeutics, 2015 - ncbi.nlm.nih.gov
Parkinson’s Disease and Its Management - PMC Back to Top Skip to main content NIH NLM
Logo Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation Search …

The burden of non-motor symptoms in Parkinson's disease using a self-completed non-motor questionnaire: a simple grading system

KR Chaudhuri, A Sauerbier, JM Rojo, K Sethi… - Parkinsonism & related …, 2015 - Elsevier
Background Non-motor symptoms (NMS) of Parkinson's disease (PD) affect virtually every
patient, yet they are under-recognized and under-treated. The NMS Questionnaire …

Disorders of the oral cavity in Parkinson's disease and parkinsonian syndromes

Y Zlotnik, Y Balash, AD Korczyn, N Giladi… - Parkinson's …, 2015 - Wiley Online Library
Awareness of nonmotor symptoms of Parkinson's disease is growing during the last decade.
Among these, oral cavity disorders are, although prevalent, often neglected by the patients …

The clinical evaluation of Parkinson's tremor

H Zach, M Dirkx, BR Bloem… - Journal of Parkinson's …, 2015 - content.iospress.com
Parkinson's disease harbours many different tremors that differ in distribution, frequency,
and context in which they occur. A good clinical tremor assessment is important for weighing …

Pain in Parkinson's disease: current concepts and a new diagnostic algorithm

V Mylius, D Ciampi de Andrade… - Movement disorders …, 2015 - Wiley Online Library
Background Pain is a significant burden for patients with Parkinson's disease (PD) with a
high impact on quality of life. The present article aims at summarizing epidemiological …

Intervention with exercise restores motor deficits but not nigrostriatal loss in a progressive MPTP mouse model of Parkinson's disease

MD Sconce, MJ Churchill, RE Greene, CK Meshul - Neuroscience, 2015 - Elsevier
Many studies have investigated exercise therapy in Parkinson's disease (PD) and have
shown benefits in improving motor deficits. However, exercise does not slow down the …

Efficacy and safety profile of prolonged release oxycodone in combination with naloxone (OXN PR) in Parkinson's disease patients with chronic pain

G Madeo, T Schirinzi, S Natoli, M Pierantozzi… - Journal of …, 2015 - Springer
Pain is a relevant and often underestimated non-motor symptom affecting the quality of life of
patients with Parkinson's disease (PD). Although some pain symptoms can be effectively …

Postural instability, the absence of sexual intercourse in the past month, and loss of libido are predictors of sexual dysfunction in Parkinson's disease

O Jitkritsadakul, P Jagota, R Bhidayasiri - Parkinsonism & related disorders, 2015 - Elsevier
Objective To determine the prevalence and predictors of sexual dysfunction (SD) in
Parkinson's disease (PD) patients. Background Assessments of SD in the professional …