Hydrogen peroxide priming modulates abiotic oxidative stress tolerance: insights from ROS detoxification and scavenging

MA Hossain, S Bhattacharjee, SM Armin… - Frontiers in plant …, 2015 - frontiersin.org
Plants are constantly challenged by various abiotic stresses that negatively affect growth
and productivity worldwide. During the course of their evolution, plants have developed …

Nanotoxicity: an interplay of oxidative stress, inflammation and cell death

P Khanna, C Ong, BH Bay, GH Baeg - Nanomaterials, 2015 - mdpi.com
Nanoparticles are emerging as a useful tool for a wide variety of biomedical, consumer and
instrumental applications that include drug delivery systems, biosensors and environmental …

[HTML][HTML] Mitochondria: are they causal players in cellular senescence?

C Correia-Melo, JF Passos - Biochimica et Biophysica Acta (BBA) …, 2015 - Elsevier
Cellular senescence entails an irreversible cell-cycle arrest characterised by drastic
cytomorphological and metabolic changes. In recent years, the implications of cellular …

The structural basis of XRCC1-mediated DNA repair

RE London - DNA repair, 2015 - Elsevier
Scaffold proteins play a central role in DNA repair by recruiting and organizing sets of
enzymes required to perform multi-step repair processes. X-ray cross complementing group …

Influenza virus replication in lung epithelial cells depends on redox‐sensitive pathways activated by NOX4‐derived ROS

D Amatore, R Sgarbanti, K Aquilano… - Cellular …, 2015 - Wiley Online Library
An overproduction of reactive oxygen species (ROS) mediated by NADPH oxidase 2 (NOX2)
has been related to airway inflammation typical of influenza infection. Virus‐induced …

[HTML][HTML] The redox biology network in cancer pathophysiology and therapeutics

G Manda, G Isvoranu, MV Comanescu, A Manea… - Redox biology, 2015 - Elsevier
The review pinpoints operational concepts related to the redox biology network applied to
the pathophysiology and therapeutics of solid tumors. A sophisticated network of intrinsic …

Licochalcone A-induced human gastric cancer BGC-823 cells apoptosis by regulating ROS-mediated MAPKs and PI3K/AKT signaling pathways

W Hao, X Yuan, L Yu, C Gao, X Sun, D Wang… - Scientific reports, 2015 - nature.com
Abstract Both phosphatidylinositol 3-kinase (PI3K)/AKT and mitogen activated protein kinase
(MAPK) signaling cascades play an important role in cell proliferation, survival …

Dieckol, isolated from the edible brown algae Ecklonia cava, induces apoptosis of ovarian cancer cells and inhibits tumor xenograft growth

JH Ahn, YI Yang, KT Lee, JH Choi - Journal of cancer research and clinical …, 2015 - Springer
Purpose Ecklonia cava is an abundant brown alga and has been reported to possess
various bioactive compounds having anti-inflammatory effect. However, the anticancer …

Protective effect of polyphenols in an inflammatory process associated with experimental pulmonary fibrosis in mice

D Impellizzeri, E Talero, R Siracusa… - British Journal of …, 2015 - cambridge.org
Polyphenols have been described to have a wide range of biological activities, and many
reports, published during recent years, have highlighted the beneficial effects of phenolic …

Effects of hydrogen-rich saline on early acute kidney injury in severely burned rats by suppressing oxidative stress induced apoptosis and inflammation

SX Guo, Q Fang, CG You, YY Jin, XG Wang… - Journal of translational …, 2015 - Springer
Background Early acute kidney injury (AKI) in severely burned patients predicts a high
mortality that is multi-factorial. Hydrogen has been reported to alleviate organ injury via …