Biomarkers for diagnosis, monitoring of progression, and treatment responses in ankylosing spondylitis and axial spondyloarthritis

JD Reveille - Clinical rheumatology, 2015 - Springer
With the growing awareness of the impact of chronic back pain and axial spondyloarthritis
and recent breakthroughs in genetics and the development of novel treatments which may …

[PDF][PDF] The genetics of osteoporosis

GR Clark, EL Duncan - Br Med Bull, 2015 - Citeseer
Introduction: Osteoporosis is the commonest metabolic bone disease worldwide. The clinical
hallmark of osteoporosis is low trauma fracture, with the most devastating being hip fracture …

[HTML][HTML] Ankylosing spondylitis: A state of the art factual backbone

M Ghasemi-Rad, H Attaya, E Lesha, A Vegh… - World journal of …, 2015 - ncbi.nlm.nih.gov
Ankylosing spondylitis (AS) is a chronic inflammatory disease that affects 1% of the general
population. As one of the most severe types of spondyloarthropathy, AS affects the spinal …

Pharmacogenomics of cyclooxygenases

JAG Agundez, M Blanca, JA Cornejo-Garcia… - …, 2015 - Taylor & Francis
Cyclooxygenases (COX-1 and COX-2) are key enzymes in several physiopathological
processes. Many adverse drugs reactions to NSAIDs are attributable to COX-inhibition. The …

Ankylosis in ankylosing spondylitis: current concepts

N Haroon - Clinical rheumatology, 2015 - Springer
Ankylosing spondylitis (AS) is the most common form of spondyloarthritis and is
characterized by both inflammation and new bone formation. Despite many years of arduous …

Increase in Dickkopf-1 serum level in recent spondyloarthritis. Data from the DESIR cohort

G Nocturne, S Pavy, S Boudaoud, R Seror, P Goupille… - PLoS …, 2015 - journals.plos.org
Objectives To investigate DKK-1 and SOST serum levels among patients with recent
inflammatory back pain (IBP) fulfilling ASAS criteria for SpA and associated factors. Methods …

Genetic variants in cyclooxygenase-2 contribute to post-treatment pain among endodontic patients

E Applebaum, AG Nackley, E Bair, W Maixner… - Journal of …, 2015 - Elsevier
Introduction Nonsteroidal anti-inflammatory drugs (NSAIDs) have a well-established
analgesic efficacy for inflammatory pain. These drugs exert their effect by inhibiting the …

Biomarkers in axial spondyloarthritis

WP Maksymowych - Current Opinion in Rheumatology, 2015 - journals.lww.com
Biomarkers in axial spondyloarthritis : Current Opinion in Rheumatology Biomarkers in axial
spondyloarthritis : Current Opinion in Rheumatology Log in or Register Subscribe to journalSubscribe …

Recent advances in imaging of the axial skeleton in spondyloarthritis for diagnosis, assessment of treatment effect, and prognostication

SJ Pedersen, WP Maksymowych - Current rheumatology reports, 2015 - Springer
In the last few years, many studies have investigated the role of imaging for improved
diagnosis, assessment of treatment effects, and determining prognosis in patients with axial …

[PDF][PDF] IL-17 INHIBITION: EMERGING PERSPECTIVES IN THE FUTURE MANAGEMENT OF AXIAL SPONDYLOARTHRITIS

A Deodhar, D Elewaut, D Baeten, X Baraliakos - emjreviews.com
Support: The symposium was jointly organised and funded by Novartis Pharmaceuticals. All
authors received honoraria for preparation and delivery of their presentations. The …