Cancer imposes a heavy societal burden worldwide, in terms of both epidemiology and
costs. The introduction of more sophisticated imaging and diagnostic techniques and …

Since the introduction of biomolecular testing for the identification of high-risk human
papillomavirus DNA (hrHPV-DNA) in cervical cancer preventive strategies, many interesting …

In the past two decades, great advances have been made in the medical care of HIV-
positive patients. This is especially evident in the pronounced increase in life expectancy …

Background Over the last two decades it has become clear that distinct types of human
papillomavirus (HPV), the so-called high-risk types (hrHPV), are the major cause of cervical …

Currently, screening for anal high‐grade squamous intraepithelial lesions (anal HSIL) relies
on anal cytology and high‐resolution anoscopy. Since this approach has limited sensitivity …

Objective: Colposcopy is widely used to triage women with mild cervical abnormalities.
However, this approach is associated with low specificity and predictive value. The efficacy …

Background Screening for anal dysplasia in human immunodeficiency virus (HIV)-infected
patients is not standardized. High-resolution imaging is not adequate for mass screening …

Background High-risk human papillomavirus (hrHPV) DNA positive women require triage
testing to identify those with high-grade cervical intraepithelial neoplasia or cancer (≥ …

In cancer treatment, non-invasive diagnosis can avoid complications of biopsy and other
unfavorable impacts on patient's health. DNA, methylation, SNPs, miRNA, mRNA, protein …

Cervical carcinoma is one of the major consequences of human papillomavirus (HPV)
infections. Although HPV infections of cervix do not always progress to cancer, 90% cases of …