Lipid membrane domains in the brain
The brain is characterized by the presence of cell types with very different functional
specialization, but with the common trait of a very high complexity of structures originated by …
specialization, but with the common trait of a very high complexity of structures originated by …
[PDF][PDF] Membrane lipid domains in the nervous system
S Sonnino, M Aureli, L Mauri, MG Ciampa… - … Biosci (Landmark Ed), 2015 - academia.edu
The structural properties of the lipids forming biological membranes determine a very high
level of lateral organization within membranes. Lipid-driven membrane organization allows …
level of lateral organization within membranes. Lipid-driven membrane organization allows …
Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology
MA Burlot, J Braudeau… - Human molecular …, 2015 - academic.oup.com
Alzheimer's disease (AD) is characterized by both amyloid and Tau pathologies. The
amyloid component and altered cholesterol metabolism are closely linked, but the …
amyloid component and altered cholesterol metabolism are closely linked, but the …
Analysis of hedgehog signaling in cerebellar granule cell precursors in a conditional Nsdhl allele demonstrates an essential role for cholesterol in postnatal CNS …
D Cunningham, AE DeBarber, N Bir… - Human molecular …, 2015 - academic.oup.com
NSDHL is a 3β-hydroxysterol dehydrogenase that is involved in the removal of two C-4
methyl groups in one of the later steps of cholesterol biosynthesis. Mutations in the gene …
methyl groups in one of the later steps of cholesterol biosynthesis. Mutations in the gene …
Neuronal specific targeting of caveolin expression to restore synaptic signaling and improve cognitive function in the neurodegenerative brain and motor function in …
US8969077B2 - Neuronal specific targeting of caveolin expression to restore synaptic signaling
and improve cognitive function in the neurodegenerative brain and motor function in spinal cord …
and improve cognitive function in the neurodegenerative brain and motor function in spinal cord …
Adenosine A2A Receptors and Neurotrophic Factors: Relevance for Parkinson's Disease
Neurotrophic factors (NTF) or drugs able to boost NTF actions have been frequently
considered as promising therapies for neurodegenerative diseases namely for Parkinson's …
considered as promising therapies for neurodegenerative diseases namely for Parkinson's …