Two-photon luminescent metal complexes for bioimaging and cancer phototherapy

Y Chen, R Guan, C Zhang, J Huang, L Ji… - Coordination Chemistry …, 2016 - Elsevier
Possessing important advantages over conventional one-photon excited emission such as
great depth discrimination and reduced photo-damage, two-photon excited emission (TPE) …

Dynamic regulation of stem cell specification and maintenance by hypoxia-inducible factors

GL Semenza - Molecular aspects of medicine, 2016 - Elsevier
Stem cells are characterized by the capacity for both self-renewal and generation of all other
cell types (pluripotency) or differentiated cells within a particular lineage (multipotency) …

[HTML][HTML] Hypoxia regulates SOX2 expression to promote prostate cancer cell invasion and sphere formation

KM Bae, Y Dai, J Vieweg… - American Journal of …, 2016 - ncbi.nlm.nih.gov
SOX2 is an embryonic stem cell marker that in prostate cancer has been associated not only
with tumorigenesis but also metastasis. Furthermore hypoxia in primary tumors has been …

[HTML][HTML] FOXM1 and STAT3 interaction confers radioresistance in glioblastoma cells

UB Maachani, U Shankavaram, T Kramp, PJ Tofilon… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Glioblastoma multiforme (GBM) continues to be the most frequently diagnosed and lethal
primary brain tumor. Adjuvant chemo-radiotherapy remains the standard of care following …

The roles of the stem cell-controlling Sox2 transcription factor: from neuroectoderm development to Alzheimer's disease?

G Sarlak, B Vincent - Molecular neurobiology, 2016 - Springer
Sox2 is a component of the core transcriptional regulatory network which maintains the
totipotency of the cells during embryonic preimplantation period, the pluripotency of …

The resveratrol analog HS-1793 enhances radiosensitivity of mouse-derived breast cancer cells under hypoxic conditions

YJ Choi, K Heo, HS Park… - … Journal of Oncology, 2016 - spandidos-publications.com
Tumor hypoxia is associated with treatment resistance, cell proliferation, and metastatic
potential, all of which contribute to a poor prognosis. Resveratrol [RES (trans-3, 4', 5 …

The impact of hypoxia and mesenchymal transition on glioblastoma pathogenesis and cancer stem cells regulation

M Karsy, J Guan, R Jensen, LE Huang, H Colman - World neurosurgery, 2016 - Elsevier
Glioblastoma (GBM) is an aggressive primary brain tumor with potential for wide
dissemination and resistance to standard treatments. Although GBM represents a single …

Iterative sorting reveals CD133+ and CD133-melanoma cells as phenotypically distinct populations

C Grasso, M Anaka, O Hofmann, R Sompallae… - BMC cancer, 2016 - Springer
Background The heterogeneity and tumourigenicity of metastatic melanoma is attributed to a
cancer stem cell model, with CD133 considered to be a cancer stem cell marker in …

The role of octamer binding transcription factors in glioblastoma multiforme

AK Rooj, A Bronisz, J Godlewski - Biochimica et Biophysica Acta (BBA) …, 2016 - Elsevier
A group of transcription factors (TF) that are master developmental regulators of the
establishment and maintenance of pluripotency during embryogenesis play additional roles …

Metabolic modification in gastrointestinal cancer stem cells: characteristics and therapeutic approaches

AM Di Francesco, A Toesca… - Journal of Cellular …, 2016 - Wiley Online Library
Currently, there is much interest in the characterization of metabolic profiling of cancer stem
cells (CSCs), a small subset of tumor cells with self‐renewal capacity. Indeed, ever‐growing …