Background Many countries are developing suicide prevention strategies for which up-to-
date, high-quality evidence is required. We present updated evidence for the effectiveness …

Depression is associated with social risk factors, social impairments and poor social
functioning. This paper gives an overview of these social aspects using the NIMH Research …

Functional bowel disorders are highly prevalent disorders found worldwide. These disorders
have the potential to affect all members of society, regardless of age, sex, race, creed, color …

In the past two decades, much evidence has accumulated unequivocally demonstrating that
child abuse and neglect is associated with a marked increase in risk for major psychiatric …

We propose that depression can be viewed as an adaptation to conserve energy after the
perceived loss of an investment in a vital resource such as a relationship, group identity, or …

In this paper, we characterize major depression (MD) as a complex dynamic system in which
symptoms (eg, insomnia and fatigue) are directly connected to one another in a network …

There is increasing recognition that many if not most common chronic pain conditions are
heterogeneous with a high degree of overlap or coprevalence of other common pain …

Research into the causes of psychopathology has largely focused on two broad etiologic
factors: genetic vulnerability and environmental stressors. An important role for …

Elevated whole blood serotonin, or hyperserotonemia, was the first biomarker identified in
autism spectrum disorder (ASD) and is present in more than 25% of affected children. The …

Resilience science is quintessential developmental psychopathology because it focuses on
variation among individuals in relation to their experiences as they adapt and develop …