TL Whiteside - Advances in clinical chemistry, 2016 - Elsevier
Tumor cells actively produce, release, and utilize exosomes to promote tumor growth. Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …
L Li, C Li, S Wang, Z Wang, J Jiang, W Wang, X Li… - Cancer research, 2016 - AACR
Hypoxia is a common feature of solid tumors and is associated with aggressiveness and poor patient outcomes. Exosomes, initially considered to be cellular “garbage dumpsters,” …
Intratumoral hypoxia is a common finding in breast cancer and is associated with a significantly increased risk of metastasis and patient mortality. Hypoxia-inducible factors …
Packed with biological information, extracellular vesicles (EVs) offer exciting promise for biomarker discovery and applications in therapeutics and non-invasive diagnostics …
Y Liu, F Luo, B Wang, H Li, Y Xu, X Liu, L Shi, X Lu… - Cancer letters, 2016 - Elsevier
Although microRNA (miRNA) enclosed in exosomes can mediate intercellular communication, the roles of exosomal miRNA and angiogenesis in lung cancer remain …
T Kang, TM Jones, C Naddell… - Stem cells …, 2016 - academic.oup.com
Cell secretion is an important mechanism for stem cell-based therapeutic angiogenesis, along with cell differentiation to vascular endothelial cells or smooth muscle cells. Cell …
KR Vrijsen, JA Maring, SAJ Chamuleau… - Advanced …, 2016 - Wiley Online Library
To date, cellular transplantation therapy has not yet fulfilled its high expectations for cardiac repair. A major limiting factor is lack of long‐term engraftment of the transplanted cells …
Exosomes are nanometer-sized extracellular vesicles that are believed to function as intercellular communicators. Here, we report that exosomes are able to modify the radiation …
SN Hurwitz, MM Conlon, MA Rider… - Journal of …, 2016 - Taylor & Francis
Background Extracellular vesicles (EVs) are important mediators of cell-to-cell communication in healthy and pathological environments. Because EVs are present in a …