[HTML][HTML] Droplet-based microfluidics in drug discovery, transcriptomics and high-throughput molecular genetics

N Shembekar, C Chaipan, R Utharala, CA Merten - Lab on a Chip, 2016 - pubs.rsc.org
Droplet-based microfluidics enables assays to be carried out at very high throughput (up to
thousands of samples per second) and enables researchers to work with very limited …

Label-free analysis and sorting of microalgae and cyanobacteria in microdroplets by intrinsic chlorophyll fluorescence for the identification of fast growing strains

RJ Best, JJ Lyczakowski, S Abalde-Cela, Z Yu… - Analytical …, 2016 - ACS Publications
Microalgae and cyanobacteria are promising organisms for sustainable biofuel production,
but several challenges remain to make this economically viable, including identification of …

[HTML][HTML] Droplet breakup in expansion-contraction microchannels

P Zhu, T Kong, L Lei, X Tian, Z Kang, L Wang - Scientific reports, 2016 - nature.com
We investigate the influences of expansion-contraction microchannels on droplet breakup in
capillary microfluidic devices. With variations in channel dimension, local shear stresses at …

[HTML][HTML] Microfluidic fabrication of hydrocortisone nanocrystals coated with polymeric stabilisers

DF Odetade, GT Vladisavljević - Micromachines, 2016 - mdpi.com
Hydrocortisone (HC) nanocrystals intended for parenteral administration of HC were
produced by anti-solvent crystallisation within coaxial assemblies of pulled borosilicate …

Microfluidic droplet trapping, splitting and merging with feedback controls and state space modelling

D Wong, CL Ren - Lab on a Chip, 2016 - pubs.rsc.org
We combine image processing and feedback controls to regulate droplet movements. A
general modelling approach is provided to describe droplet motion in a pressure-driven …

[HTML][HTML] A mix-and-read drop-based in vitro two-hybrid method for screening high-affinity peptide binders

N Cui, H Zhang, N Schneider, Y Tao, H Asahara… - Scientific Reports, 2016 - nature.com
Drop-based microfluidics have recently become a novel tool by providing a stable linkage
between phenotype and genotype for high throughput screening. However, use of drop …

Splitting droplets in a channel by help of surface acoustic wave

LW Dong, YL Hu, YF Han, AL Zhang - Ferroelectrics, 2016 - Taylor & Francis
ABSTRACT A new method for splitting droplets in a channel was presented. Two interdigital
transducers were fabricated on a 1280 yx-LiNbO3 substrate using microelectrical …

Non-textured laser modification of silica glass surface: Wettability control and flow channel formation

Y Aono, A Hirata, H Tokura - Applied Surface Science, 2016 - Elsevier
Local wettability of silica glass surface is modified by infrared laser irradiation. The silica
glass surface exhibits hydrophobic property in the presence of single bondCF 3 or single …

Integrated microfluidic system with simultaneous emulsion generation and concentration

KS Koppula, R Fan, KR Veerapalli, J Wan - Journal of colloid and interface …, 2016 - Elsevier
Because the size, size distribution, and concentration of emulsions play an important role in
most of the applications, controlled emulsion generation and effective concentration are of …

Microfluidic chip for rapid mixing and uniform distribution of multiple reagents using commercial pipettes

PC Chen, YC Chen, CM Tsai - Microelectronic Engineering, 2016 - Elsevier
The mixing and distribution of reagents are fundamental processes in most biochemical
experiments; however, they can be time-consuming when they are executed with manual …