Low‐level vagus nerve stimulation attenuates myocardial ischemic reperfusion injury by antioxidative stress and antiapoptosis reactions in Canines

M Chen, X Zhou, L Yu, Q Liu, X Sheng… - Journal of …, 2016 - Wiley Online Library
Vagus Nerve Stimulation and Myocardial Ischemia‐Reperfusion Injury Background Low‐
level vagus nerve stimulation (LL‐VNS) has been demonstrated to protect myocardium …

Water-soluble acacetin prodrug confers significant cardioprotection against ischemia/reperfusion injury

H Liu, L Yang, HJ Wu, KH Chen, F Lin, G Li, HY Sun… - Scientific Reports, 2016 - nature.com
The morbidity and mortality of patients with ischemic cardiomyopathy resulted from
ischemia/reperfusion injury are very high. The present study investigates whether our …

Effects of relaxin on cardiac fibrosis, apoptosis, and tachyarrhythmia in rats with myocardial infarction

D Wang, H Zhu, Q Yang, Y Sun - Biomedicine & Pharmacotherapy, 2016 - Elsevier
Relaxin is safe and efficient to use for treating acute heart failure. However, the
electrophysiological and arrhythmogenic effects of relaxin in an experimental healing …

The effects of pentobarbital, ketamine–pentobarbital and ketamine–xylazine anesthesia in a rat myocardial ischemic reperfusion injury model

S Shekarforoush, Z Fatahi, F Safari - Laboratory animals, 2016 - journals.sagepub.com
To achieve reliable experimental data, the side-effects of anesthetics should be eliminated.
Since anesthetics exert a variety of effects on hemodynamic data and incidence of …

Noninvasive low-frequency electromagnetic stimulation of the left stellate ganglion reduces myocardial infarction-induced ventricular arrhythmia

S Wang, X Zhou, B Huang, Z Wang, L Zhou, M Wang… - Scientific reports, 2016 - nature.com
Noninvasive magnetic stimulation has been widely used in autonomic disorders in the past
few decades, but few studies has been done in cardiac diseases. Recently, studies showed …

Lumbrokinase attenuates myocardial ischemia-reperfusion injury by inhibiting TLR4 signaling

YH Wang, KM Chen, PS Chiu, SC Lai, HH Su… - Journal of molecular and …, 2016 - Elsevier
Lumbrokinase, a novel antithrombotic agent, purified from the earthworm Lumbricus
rubellus, has been clinically used to treat stroke and cardiovascular diseases. However …

Antiarrhythmic effect of growth factor-supplemented cardiac progenitor cells in chronic infarcted heart

M Savi, L Bocchi, S Rossi, C Frati… - American Journal …, 2016 - journals.physiology.org
c-Kitpos cardiac progenitor cells (CPCs) represent a successful approach in healing the
infarcted heart and rescuing its mechanical function, but electrophysiological consequences …

Remote vs. local ischaemic preconditioning in the rat heart: infarct limitation, suppression of ischaemic arrhythmia and the role of reactive oxygen species

MM Galagudza, DL Sonin, TD Vlasov… - International Journal …, 2016 - Wiley Online Library
The unmet clinical need for myocardial salvage during ischaemia–reperfusion injury
requires the development of new techniques for myocardial protection. In this study the …

Loss of the transcription factor Meis1 prevents sympathetic neurons target-field innervation and increases susceptibility to sudden cardiac death

F Bouilloux, J Thireau, S Venteo, C Farah, S Karam… - Elife, 2016 - elifesciences.org
Although cardio-vascular incidents and sudden cardiac death (SCD) are among the leading
causes of premature death in the general population, the origins remain unidentified in …

The HNO donor Angeli's salt offers potential haemodynamic advantages over NO or dobutamine in ischaemia–reperfusion injury in the rat heart ex vivo

KY Chin, L Michel, CX Qin, N Cao, OL Woodman… - Pharmacological …, 2016 - Elsevier
Available inotropic pharmacotherapy for acute heart failure (HF) remains largely ineffective
at ameliorating marked impairments in contractile function. Nitroxyl (HNO), the redox sibling …