This review attempts to give a concise and up-to-date overview on the role of potassium
channels in epilepsies. Their role can be defined from a genetic perspective, focusing on …

GABAergic interneurons of the parvalbumin-positive fast-spiking basket cells subtype (PV
INs) are important regulators of cortical network excitability and of gamma oscillations …

Cortical fast-spiking (FS) neurons generate high-frequency action potentials (APs) without
apparent frequency accommodation, thus providing fast and precise inhibition. However, the …

Clinical and pre-clinical evidence has implicated neuregulin 1 (NRG1) as a critical
component in the pathophysiology of schizophrenia. However, the arrival of the genome …

Objective: Alternative splicing of ErbB4 transcripts is dysregulated in the dorsolateral
prefrontal cortex in schizophrenia. ErbB4 regulates the activity of parvalbumin interneurons …

Maturation of excitatory drive onto fast-spiking interneurons (FS INs) in the visual cortex has
been implicated in the control of the timing of the critical period for ocular dominance …

Rapid impulse propagation in the heart is a defining property of pectinated atrial
myocardium (PAM) and the ventricular conduction system (VCS) and is essential for …

Recent reports in human demonstrate a role of theta–gamma coupling in memory for spatial
episodes and a lack of coupling in people experiencing temporal lobe epilepsy, but the …

The purpose of the present study was to investigate the possible association between
temporal lobe epilepsy and NRG1 gene polymorphisms. A total of 73 patients and 69 …

Disturbance of neuregulin-1β/ErbB4 signaling is considered to be associated with brain
ischemia, but the mechanisms of this disruption are largely unknown. In the present study …