It is predicted that Japan and European Union will soon experience appreciable decreases
in their populations due to persistently low total fertility rates (TFR) below replacement level …

The study aims to discuss the effects of aging on the male reproductive system. A systematic
review was performed using PubMed from 1980 to 2014. Aging is a natural process …

Objective: To formulate clinical practice guidelines for hormonal replacement in
hypopituitarism in adults. Participants: The participants include an Endocrine Society …

Key points Resistance exercise training (RET) is one of the most effective strategies for
preventing declines in skeletal muscle mass and strength with age. Hypertrophic responses …

Skeletal muscles comprise a substantial portion of whole body mass and are integral for
locomotion and metabolic health. Increasing age is associated with declines in both muscle …

BACKGROUND. Severe gonadal steroid deficiency induces bone loss in adult men;
however, the specific roles of androgen and estrogen deficiency in hypogonadal bone loss …

Reproductive function changes markedly during life in humans. Impeccable coordination of
the hypothalamic-pituitary-gonadal axis is required for normal testicular function in the male …

Context: The Testosterone Trials are a coordinated set of seven trials to determine the
efficacy of T in symptomatic men≥ 65 years old with unequivocally low T levels. Initial …

Abstract Introduction: This article, Part 1 of the Endocrine Society of Australia's position
statement on male hypogonadism, focuses on assessment of male hypogonadism, including …

Abstract Male factor contributes to 50%–60% of overall infertility but is solely responsible in
only 20% of couples. Although most male factor infertility is ascertained from an abnormal …