Clinical and pre-clinical evidence has implicated neuregulin 1 (NRG1) as a critical
component in the pathophysiology of schizophrenia. However, the arrival of the genome …

Schizophrenia has long been considered as a disorder with multifactorial origins. Recent
discoveries have advanced our understanding of the genetic architecture of the disease …

The study of gene× environment, as well as epistatic interactions in schizophrenia, has
provided important insight into the complex etiopathologic basis of schizophrenia. It has also …

Sex differences in schizophrenia are apparent in almost all features of the illness, from
incidence and mean age of onset to symptomatology, course of illness and response to …

Background Maternal iron deficiency and infection during pregnancy have individually been
associated with increased risk of schizophrenia in the offspring, but possible interactions …

Adverse environmental factors including prenatal maternal infection are capable of inducing
long-lasting behavioral and neural alterations which can enhance the risk to develop …

Genetic association approaches and the more recent contributions from genome-wide
association studies have identified a number of risk genes for schizophrenia that potentially …

Schizophrenia is a mental disorder of a multifactorial origin that involves both genetic and
environmental influences. Technological innovations and recent discoveries in genetics …

Maternal immune activation (MIA) is an important environmental risk factor for
schizophrenia. Among various modes of MIA, modeling maternal viral infection by injecting …

Advances in Schizophrenia Research Page 1 Animal Models of Schizophrenia: An Update
Valentine Bouet*; Michel Boulouard; Thomas Freret Normandie Univ, Unicaen, Inserm …