Breast tumors grow in a tissue microenvironment containing extracellular matrix (ECM),
adipocytes, stromal cells, fluids, and blood vessels. This natural yet complex …

Hydrogen sulfide (H2S), together with nitric oxide and carbon monoxide, has been
recognized as an important gasotransmitter. It plays an essential physiological role in …

To mimic the structure of breast tumor microenvironment, novel double-network poly (N ɛ-
acryloyl l-lysine)/hyaluronic acid (pLysAAm/HA) hydrogels were fabricated by a two-step …

The cancer stem cell (CSC) population displays self-renewal capabilities, resistance to
conventional therapies, and a tendency to post-treatment recurrence. Increasing knowledge …

Abstract Three-dimensional (3D) customized scaffolds capable to mimic a native
extracellular matrix open new frontiers in cells manipulation and advanced therapy. The …

Abstract Fused Deposition Model (FDM) as Additive manufacturing (AM) technologies may
offer a viable and simpler alternative to manufacture scaffolds for different purposes such as …

Stem cells have the ability to self-renew and differentiate into specialized cell types, and, in
the human body, they reside in specialized microenvironments called “stem cell niches.” …

Electrospinning technology is a simple, convenient, and cost-effective method to fabricate
nano/micro fibrous materials. Electrospun fibers are generally collected as a two …

The most common in vitro cell culture platform, standard two-dimensional (2D) monolayer
cell culture, often fails to mimic the tumor microenvironment, while animal models complicate …

Cell-based medicine is recently attracting extensive attention as a potential therapeutic
approach for various diseases. However, major hurdles have prevented their widespread …