Cannabis use has been reported to induce long-lasting psychotic disorders and a dose-
response relationship has been observed. We performed a systematic review of studies that …

With a political debate about the potential risks and benefits of cannabis use as a backdrop,
the wave of legalization and liberalization initiatives continues to spread. Four states …

Cannabis is globally the most commonly used psychoactive substance under international
control. In 2013, an estimated 181.8 million people aged 15− 64 years used cannabis for …

Cannabis use has been associated with impaired cognition during acute intoxication as well
as in the unintoxicated state in long-term users. However, the evidence has been mixed and …

Associations between cannabis use and psychotic outcomes are consistently reported, but
establishing causality from observational designs can be problematic. We review the …

Epidemiological evidence demonstrates that cannabis use is associated with an increased
risk of psychotic outcomes, and confirms a dose‐response relationship between the level of …

Objectives: Cannabis use is prevalent among people with first episode psychosis and the
epidemiology of its use in early psychosis is unclear. We performed a meta-analysis of …

Background Adolescence represents a period of development during which critical
biological, as well as social and cognitive, changes occur that are necessary for the …

There is urgent need for the development of mechanistically different and less side-effect
prone antipsychotic compounds. The endocannabinoid system has been suggested to …

Importance After major policy changes in the United States, policymakers, health care
professionals, and the general public seek information about whether recreational cannabis …