[HTML][HTML] Chemically induced skin carcinogenesis: Updates in experimental models

M Neagu, C Caruntu, C Constantin… - Oncology …, 2016 - … .spandidos-publications.com
Skin cancer is one of the most common malignancies affecting humans worldwide, and its
incidence is rapidly increasing. The study of skin carcinogenesis is of major interest for both …

The dark side of the light: mechanisms of photocarcinogenesis

MMV Coelho, TR Matos, M Apetato - Clinics in dermatology, 2016 - Elsevier
Ultraviolet radiation (UVR) can have a beneficial biologic impact on skin, but it is also the
most significant environmental risk factor for skin cancer development. Photocarcinogenesis …

[HTML][HTML] Galectin-7 regulates keratinocyte proliferation and differentiation through JNK-miR-203-p63 signaling

HL Chen, PC Chiang, CH Lo, YH Lo, DK Hsu… - Journal of Investigative …, 2016 - Elsevier
Galectin-7, a member of the β-galactoside-binding protein family, is primarily expressed in
stratified epithelial cells, including keratinocytes. There is information in the literature …

Desired response to phototherapy vs photoaggravation in psoriasis: what makes the difference?

P Wolf, W Weger, VK Patra… - Experimental …, 2016 - Wiley Online Library
Psoriasis commonly responds beneficially to UV radiation from natural sunlight or artificial
sources. Therapeutic mechanisms include the proapoptotic and immunomodulating effects …

Mechanism of action of flavonoids in prevention of inflammation-associated skin cancer

V Cijo George, V Vijayakumaran Vijesh… - Current Medicinal …, 2016 - ingentaconnect.com
Skin cancer in humans represents about 30% of all new cancers and is by far the most
common malignancy in the Caucasian population. Exposure to radiations especially …

MiR-137 affects melanin synthesis in mouse melanocyte by repressing the expression of c-Kit and Tyrp2 in SCF/c-Kit signaling pathway

S Jiang, X Yu, C Dong - Bioscience, Biotechnology, and …, 2016 - academic.oup.com
Previously, we created miR-137 overexpressing transgenic mice that produced lighten color
phenotypes including gray mice phenotype. However, the miR-137 functional role in coat …

The response of microRNAs to solar UVR in skin-resident melanocytes differs between melanoma patients and healthy persons

J Sha, BR Gastman, N Morris, NA Mesinkovska… - PLoS …, 2016 - journals.plos.org
The conversion of melanocytes into cutaneous melanoma is largely dictated by the effects of
solar ultraviolet radiation (UVR). Yet to be described, however, is exactly how these cells are …

Association between Toll-like receptor 7 Gln11Leu single-nucleotide polymorphism and basal cell carcinoma

I Russo, C Cona, A Saponeri… - Biomedical …, 2016 - spandidos-publications.com
Non-melanoma skin cancers (NMSC) are the most common form of human skin cancer. The
majority of NMSC are basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) with …

中波紫外线致皮肤色素沉着及其相关机制的研究进展

妥亚楠, 李承新 - 解放军医学院学报, 2016 - xuebao.301hospital.com.cn
人类表皮色素沉着是对紫外线照射的一种适应机制, 皮肤在各种内外因素的影响下,
通过色素沉着形成防御系统来对抗日光照射. 色素沉着主要由日光中的中波紫外线(ultraviolet B …

Hsa-miR-520d-5p promotes survival in human dermal fibroblasts exposed to a lethal dose of UV irradiation

Y Ishihara, S Tsuno, B Ping, T Ashizaki… - npj Aging and …, 2016 - nature.com
We previously reported that hsa-miR-520d-5p is functionally involved in the induction of the
epithelial–mesenchymal transition and stemness-mediated processes in normal cells and …