[HTML][HTML] Defining patient centric pharmaceutical drug product design

S Stegemann, RL Ternik, G Onder, MA Khan… - The AAPS journal, 2016 - Springer
Abstract The term “patient centered,”“patient centric,” or “patient centricity” is increasingly
used in the scientific literature in a wide variety of contexts. Generally, patient centric …

Polypharmacy and effects of apixaban versus warfarin in patients with atrial fibrillation: post hoc analysis of the ARISTOTLE trial

JJ Focks, MA Brouwer, DM Wojdyla, L Thomas… - Bmj, 2016 - bmj.com
Objective To determine whether the treatment effect of apixaban versus warfarin differs with
increasing numbers of concomitant drugs used by patients with atrial fibrillation. Design Post …

Acute bacterial skin and skin structure infections in internal medicine wards: old and new drugs

M Falcone, E Concia, M Giusti, A Mazzone… - Internal and emergency …, 2016 - Springer
Skin and soft tissue infections (SSTIs) are a common cause of hospital admission among
elderly patients, and traditionally have been divided into complicated and uncomplicated …

Polypharmacy and major adverse events in atrial fibrillation: observations from the AFFIRM trial

M Proietti, V Raparelli, B Olshansky… - Clinical Research in …, 2016 - Springer
Background Polypharmacy, as the use of five or more drugs, has commonly been
associated with the elderly and multiple co-morbidities and related to impairment of clinical …

[HTML][HTML] Pilot study to test the feasibility of a trial design and complex intervention on PRIoritising MUltimedication in Multimorbidity in general practices (PRIMUMpilot)

C Muth, S Harder, L Uhlmann, J Rochon, B Fullerton… - BMJ open, 2016 - bmjopen.bmj.com
Objective To improve medication appropriateness and adherence in elderly patients with
multimorbidity, we developed a complex intervention involving general practitioners (GPs) …

The future of pharmaceutical manufacturing in the context of the scientific, social, technological and economic evolution

S Stegemann - European Journal of Pharmaceutical Sciences, 2016 - Elsevier
Healthcare provision is one of the import elements of modern societies. Life sciences and
technology has made substantial progress over the past century and is continuing to evolve …

The psychosocial challenges and care of older adults with diabetes:“Can't do what I used to do; can't be who I once was”

EA Beverly, MD Ritholz, C Shepherd… - Current diabetes reports, 2016 - Springer
The prevalence of diabetes is increasing in older populations worldwide. Older adults with
diabetes have unique psychosocial and medical challenges that impact self-care and …

The challenges of treating sciatica pain in older adults

ML Ferreira, A McLachlan - Drugs & aging, 2016 - Springer
Sciatica is a debilitating condition affecting approximately 25% of the population. Typically,
the patient will complain of lower limb pain that is more severe than pain in the lower back …

The management of polypharmacy in people with cancer and chronic conditions

JP Turner, RA McKinnon, JS Bell - … the Problem of Multimorbidity in Cancer …, 2016 - Springer
Polypharmacy has a broad definition, encompassing the use of multiple medications, the
use of more medications than necessary, or the use of inappropriate medications …

Polimedicação no idoso

MTAAP Lavrador - 2016 - estudogeral.uc.pt
O envelhecimento gradual da população e o aumento da esperança de vida conduzem a
uma maior prevalência de patologias crónicas nos idosos, levando a que estes constituam …