NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …
J Dose, P Huebbe, A Nebel, G Rimbach - Lipids in health and disease, 2016 - Springer
The APOE gene is one of currently only two genes that have consistently been associated with longevity. Apolipoprotein E (APOE) is a plasma protein which plays an important role in …
JB Lin, N Mast, IR Bederman, Y Li… - Journal of lipid …, 2016 - ASBMB
The retina, a thin tissue in the back of the eye, has two apparent sources of cholesterol: in situ biosynthesis and cholesterol available from the systemic circulation. The quantitative …
The cholesterol transporting protein apolipoprotein E (ApoE) occurs in three allelic variants in humans unlike in other species. The resulting protein isoforms E2, E3 and E4 exhibit …
Purpose Demographic, environmental, and genetic risk factors for age-related macular degeneration (AMD) have been identified; however, a substantial portion of the variance in …
C Wright, J Ambati - Advances in Geroscience, 2016 - Springer
Age-related macular degeneration (AMD) is a major contributing factor to non-reversible vision loss in the aging population in the developed world, but as of yet, it is still a poorly …
The Regulation of AMD Pathobiology by Complement Factor H by Christopher B. Toomey Department of Cell Biology Duke University Da Page 1 The Regulation of AMD …