Epidemiology of age-related macular degeneration (AMD): associations with cardiovascular disease phenotypes and lipid factors

KL Pennington, MM DeAngelis - Eye and vision, 2016 - Springer
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in
adults over 50 years old. Genetic, epidemiological, and molecular studies are beginning to …

Risk factors and biomarkers of age-related macular degeneration

NG Lambert, H ElShelmani, MK Singh… - Progress in retinal and …, 2016 - Elsevier
A biomarker can be a substance or structure measured in body parts, fluids or products that
can affect or predict disease incidence. As age-related macular degeneration (AMD) is the …

APOE genotype and stress response - a mini review

J Dose, P Huebbe, A Nebel, G Rimbach - Lipids in health and disease, 2016 - Springer
The APOE gene is one of currently only two genes that have consistently been associated
with longevity. Apolipoprotein E (APOE) is a plasma protein which plays an important role in …

Cholesterol in mouse retina originates primarily from in situ de novo biosynthesis

JB Lin, N Mast, IR Bederman, Y Li… - Journal of lipid …, 2016 - ASBMB
The retina, a thin tissue in the back of the eye, has two apparent sources of cholesterol: in
situ biosynthesis and cholesterol available from the systemic circulation. The quantitative …

[图书][B] Apolipoprotein E isoforms and AMD

KA Toops, LX Tan, A Lakkaraju - 2016 - Springer
The cholesterol transporting protein apolipoprotein E (ApoE) occurs in three allelic variants
in humans unlike in other species. The resulting protein isoforms E2, E3 and E4 exhibit …

[HTML][HTML] Whole exome sequencing of extreme age-related macular degeneration phenotypes

RJ Sardell, JNC Bailey, MD Courtenay… - Molecular …, 2016 - ncbi.nlm.nih.gov
Purpose Demographic, environmental, and genetic risk factors for age-related macular
degeneration (AMD) have been identified; however, a substantial portion of the variance in …

[HTML][HTML] 叶黄素生物利用与脂类相关性研究进展

黄雪, 应威, 徐贤荣 - Hans Journal of Food and Nutrition Science, 2016 - hanspub.org
叶黄素是一种脂溶性类胡萝卜素, 广泛存在于绿叶蔬菜, 鸡蛋等食物中. 其在人体中的整个生物
利用过程, 包括消化, 吸收, 运输, 代谢等过程均与脂类有密切关系. 膳食叶黄素的消化吸收需要多 …

Age-Related Macular Degeneration and Vision Impairment

C Wright, J Ambati - Advances in Geroscience, 2016 - Springer
Age-related macular degeneration (AMD) is a major contributing factor to non-reversible
vision loss in the aging population in the developed world, but as of yet, it is still a poorly …

Плейотропия при многофакторных заболеваниях и подходы к ее оценке

АА Слепцов, МС Назаренко - … -БИОЛОГИЧЕСКИЕ ТЕХНОЛОГИИ В …, 2016 - elibrary.ru
Плейотропия–это результат влияния одного гена на несколько признаков. Большое
количество проведенных полногеномных ассоциативных исследований (GWAS) …

[PDF][PDF] The Regulation of AMD Pathobiology by Complement Factor H

CB Toomey - 2016 - dukespace.lib.duke.edu
The Regulation of AMD Pathobiology by Complement Factor H by Christopher B. Toomey
Department of Cell Biology Duke University Da Page 1 The Regulation of AMD …