Time-to-onset analysis of drug-induced long QT syndrome based on a spontaneous reporting system for adverse drug events

S Sasaoka, T Matsui, Y Hane, J Abe, N Ueda… - PLoS …, 2016 - journals.plos.org
Long QT syndrome (LQTS) is a disorder of the heart's electrical activity that infrequently
causes severe ventricular arrhythmias such as a type of ventricular tachycardia called …

Pharmacogenetics of potassium channel blockers

DM Roden - Cardiac electrophysiology clinics, 2016 - cardiacep.theclinics.com
Drugs vary in their effects for many reasons, such as incomplete compliance, the underlying
disease being treated, clinical covariates such as age and sex, and interaction with other …

Genetic variation in the miR‐708 gene and its binding targets in bipolar disorder

A Fiorentino, NL O'Brien, SI Sharp, D Curtis… - Bipolar …, 2016 - Wiley Online Library
Objective rs12576775 was found to be associated with bipolar disorder (BD) in a genome‐
wide association study (GWAS). The GWAS signal implicates genes for the microRNAs miR …

A novel relationship for schizophrenia, bipolar and major depressive disorder part 6: a hint from chromosome 6 high density association screen

X Chen, F Long, B Cai, XH Chen… - Current molecular …, 2016 - ingentaconnect.com
Background: Convergent evidence from genetics, symptomatology and
psychopharmacology imply that there are intrinsic connections between schizophrenia …

Pharmacogenomics: A focus on antidepressants and atypical antipsychotics

JF Lister - Mental Health Clinician, 2016 - meridian.allenpress.com
The study of pharmacogenomics is rapidly growing, particularly in the field of mental health.
Understanding pharmacogenomic principles can be a challenge for many clinicians. Most …

Psychiatric pharmacogenomics: translating genomics

RH Perlis - Genomics, Circuits, and Pathways in Clinical …, 2016 - Elsevier
Pharmacogenomics describes the influence of genetic variation on any aspect of drug
response. The heritability of such phenotypes for psychiatric medications is not well …

Pharmacogenomics of ventricular conduction in multi-ethnic populations

AA Seyerle - 2016 - search.proquest.com
Adverse drug reactions (ADRs) pose a serious public health burden, yet the role of genetics
in drug response remains incompletely characterized. Thiazide diuretics, commonly used …

QTc Prolongation Associated With Psychotropics: Therapeutic Considerations.

MB McCorkle, NB Washington, NC Brahm… - Psychiatric …, 2016 - search.ebscohost.com
The article discusses a continuing medical education (CME) activity that focuses on the
importance of corrected QT or QTc monitoring in patients receiving psychotropics, especially …

[引用][C] Prolongación del intervalo QTc asociada a psicotrópicos: consideraciones terapéuticas

MB McCorkle, NB Washington, NC Brahm - terapéutica