The therapeutic voyage of pyrazole and its analogs: a review
Pyrazole, a five membered heteroaromatic ring with two nitrogen atoms is of immense
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
significance. Presence of this nucleus in the pharmacological agents of diverse therapeutic …
Enantioselective Synthesis of Spirocyclohexadienones by NHC‐Catalyzed Formal [3+ 3] Annulation Reaction of Enals
The enantioselective synthesis of pyrazolone‐fused spirocyclohexadienones was
demonstrated by the reaction of α, β‐unsaturated aldehydes with α‐arylidene pyrazolinones …
demonstrated by the reaction of α, β‐unsaturated aldehydes with α‐arylidene pyrazolinones …
Radical addition of hydrazones by α-bromo ketones to prepare 1, 3, 5-trisubstituted pyrazoles via visible light catalysis
A novel efficient tandem reaction of hydrazones and α-bromo ketones is reported for the
preparation of 1, 3, 5-trisubstituted pyrazoles by visible light catalysis. In this system, the …
preparation of 1, 3, 5-trisubstituted pyrazoles by visible light catalysis. In this system, the …
Synthesis, cytotoxicity and carbonic anhydrase inhibitory activities of new pyrazolines
K Kucukoglu, F Oral, T Aydin, C Yamali… - Journal of enzyme …, 2016 - Taylor & Francis
A series of polymethoxylated-pyrazoline benzene sulfonamides were synthesized,
investigated for their cytotoxic activities on tumor and non-tumor cell lines and inhibitory …
investigated for their cytotoxic activities on tumor and non-tumor cell lines and inhibitory …
Synthesis and bioactivities of novel pyrazole oxime derivatives containing a 1, 2, 3-thiadiazole moiety
H Dai, S Ge, G Li, J Chen, Y Shi, L Ye, Y Ling - Bioorganic & Medicinal …, 2016 - Elsevier
A series of new pyrazole oxime compounds bearing a 1, 2, 3-thiadiazole ring were
designed, synthesized, and evaluated for their insecticidal, acaricidal and antitumor …
designed, synthesized, and evaluated for their insecticidal, acaricidal and antitumor …
Cycloisomerization of acetylenic oximes and hydrazones under gold catalysis: Synthesis and cytotoxic evaluation of isoxazoles and pyrazoles
The synthesis of substituted isoxazoles and pyrazoles through a general cycloisomerization
methodology has been reported. The capability of gold (III) chloride to promote …
methodology has been reported. The capability of gold (III) chloride to promote …
MoO 2 Cl 2 catalyzed efficient synthesis of functionalized 3, 4-dihydropyrimidin-2 (1 H)-ones/thiones and polyhydroquinolines: recyclability, fluorescence and …
A simple, facile and efficient synthesis of functionalized dihydropyrimidinones and
polyhydroquinolines using molybdenum (VI) dichloride dioxide (MoO2Cl2) has been …
polyhydroquinolines using molybdenum (VI) dichloride dioxide (MoO2Cl2) has been …
Synthesis of (Z)-1-(1, 3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino) prop-2-en-1-one derivatives as potential anticancer and apoptosis inducing agents
Abstract A series of (Z)-1-(1, 3-diphenyl-1H-pyrazol-4-yl)-3-(phenylamino) prop-2-en-1-one
derivatives were synthesized and characterized by 1 H and 13 C NMR, ESI-MS and HRMS …
derivatives were synthesized and characterized by 1 H and 13 C NMR, ESI-MS and HRMS …
One-pot synthesis of 4-(phenylselanyl)-substituted pyrazoles
A facile, one-pot, general synthetic method for the preparation of 4-(phenylselanyl)
pyrazoles is described. When reacted with hydrazines, α, β-alkynic aldehydes produced in …
pyrazoles is described. When reacted with hydrazines, α, β-alkynic aldehydes produced in …
A facile and expeditious approach to substituted 1H-pyrazoles catalyzed by iodine
H Zhang, Q Wei, G Zhu, J Qu, B Wang - Tetrahedron Letters, 2016 - Elsevier
A facile and expeditious method for the synthesis of 1H-pyrazoles by the reaction of α, β-
unsaturated aldehydes/ketones and sulfonyl hydrazide catalyzed by as low as 2 mol% I 2 …
unsaturated aldehydes/ketones and sulfonyl hydrazide catalyzed by as low as 2 mol% I 2 …