SARS and MERS: recent insights into emerging coronaviruses
E De Wit, N Van Doremalen, D Falzarano… - Nature reviews …, 2016 - nature.com
Abstract The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in
2012 marked the second introduction of a highly pathogenic coronavirus into the human …
2012 marked the second introduction of a highly pathogenic coronavirus into the human …
Epidemiology, genetic recombination, and pathogenesis of coronaviruses
Human coronaviruses (HCoVs) were first described in the 1960s for patients with the
common cold. Since then, more HCoVs have been discovered, including those that cause …
common cold. Since then, more HCoVs have been discovered, including those that cause …
Coronaviruses—drug discovery and therapeutic options
In humans, infections with the human coronavirus (HCoV) strains HCoV-229E, HCoV-OC43,
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
HCoV-NL63 and HCoV-HKU1 usually result in mild, self-limiting upper respiratory tract …
Dysregulated type I interferon and inflammatory monocyte-macrophage responses cause lethal pneumonia in SARS-CoV-infected mice
Highly pathogenic human respiratory coronaviruses cause acute lethal disease
characterized by exuberant inflammatory responses and lung damage. However, the factors …
characterized by exuberant inflammatory responses and lung damage. However, the factors …
Middle East respiratory syndrome coronavirus causes multiple organ damage and lethal disease in mice transgenic for human dipeptidyl peptidase 4
K Li, C Wohlford-Lenane, S Perlman… - The Journal of …, 2016 - academic.oup.com
Middle East respiratory syndrome coronavirus (MERS-CoV) causes life-threatening disease.
Dipeptidyl peptidase 4 (DPP4) is the receptor for cell binding and entry. There is a need for …
Dipeptidyl peptidase 4 (DPP4) is the receptor for cell binding and entry. There is a need for …
Co-circulation of three camel coronavirus species and recombination of MERS-CoVs in Saudi Arabia
Outbreaks of Middle East respiratory syndrome (MERS) raise questions about the
prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our …
prevalence and evolution of the MERS coronavirus (CoV) in its animal reservoir. Our …
Viral shedding and antibody response in 37 patients with Middle East respiratory syndrome coronavirus infection
Abstract Background. The Middle East respiratory syndrome (MERS) coronavirus causes
isolated cases and outbreaks of severe respiratory disease. Essential features of the natural …
isolated cases and outbreaks of severe respiratory disease. Essential features of the natural …
An orthopoxvirus-based vaccine reduces virus excretion after MERS-CoV infection in dromedary camels
Middle East respiratory syndrome coronavirus (MERS-CoV) infections have led to an
ongoing outbreak in humans, which was fueled by multiple zoonotic MERS-CoV …
ongoing outbreak in humans, which was fueled by multiple zoonotic MERS-CoV …
[HTML][HTML] Persistence of antibodies against Middle East respiratory syndrome coronavirus
DC Payne, I Iblan, B Rha, S Alqasrawi… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
To determine how long antibodies against Middle East respiratory syndrome coronavirus
persist, we measured long-term antibody responses among persons serologically positive or …
persist, we measured long-term antibody responses among persons serologically positive or …
Environmental contamination and viral shedding in MERS patients during MERS-CoV outbreak in South Korea
SY Bin, JY Heo, MS Song, J Lee, EH Kim… - Clinical infectious …, 2016 - academic.oup.com
Abstract Background. Although Middle East Respiratory Syndrome coronavirus (MERS-
CoV) is characterized by a risk of nosocomial transmission, the detailed mode of …
CoV) is characterized by a risk of nosocomial transmission, the detailed mode of …