Many patients with epilepsy do not obtain proper control of their seizures through
conventional treatment. We review aspects of the pathophysiology underlying epileptic …

Epilepsy, one of the most prevalent neurological disorders, affects approximately 1%(greater
than 60 million) of the world's population. In an estimated 20 million of these patients …

High-frequency stimulation (HFS) of the anterior nucleus of thalamus (ANT) is a new and
alternative option for the treatment of intractable epilepsy. However, the responder rate is …

Electrical stimulation in the treatment of epilepsy has been tried in numerous forms and with
a variety of targets. Some of these, such as anterior thalamic stimulation, responsive cortical …

Low frequency stimulation (LFS) has been proposed as a new approach in the treatment of
epilepsy. The anticonvulsant mechanism of LFS may be through its effect on GABA A …

High-frequency oscillations (HFOs) are promising biomarkers for epileptic foci; however,
their characteristic changes during the preictal period remain unclear. Here, the preictal …

Although clinical trials in refractory epilepsy are currently carried out, the field of deep brain
stimulation (DBS) in epilepsy is still at its initial stage. Little is known about where, when and …

1. Introduction pilepsyis known as a common neurological disorder affecting about one
percent of the world's population (Zhang, Franklin, & Murray, 1993). The most common …

Background and purpose: Low frequency stimulation (LFS) has anticonvulsant effect.
However, its mechanism of action has not been completely determined. In the present study …

زمینه و هدف: تحریک الکتریکی کم فرکانس (LFS) دارای اثرات ضد تشنجی است که مکانیسم
عملکرد آن به درستی مشخص نشده است. هدف مطالعه حاضر بررسی اثر اعمال LFS بر جریان های …‎