In the past two decades, much evidence has accumulated unequivocally demonstrating that
child abuse and neglect is associated with a marked increase in risk for major psychiatric …

Objectives: Converging evidence suggests that the sequelae of adverse childhood
experiences (ACEs) including childhood abuse (eg, sexual, physical, emotional/verbal …

BackgroundMajor depressive disorder (MDD) is a common and disabling condition with well-
established heritability and environmental risk factors. Gene–environment interaction …

Psychiatric disorders are excellent disease models in which gene–environmental interaction
play a significant role in the pathogenesis. Childhood trauma has been known as a …

Translational research focuses on innovation in healthcare settings, but this is a two-way
process that may have implications for either treatment or prevention. Smoking and lung …

J amie Gajos, Abigail Fagan, and Kevin Beaver (2016: 683-701) in their target article point
out that over the last decade, candidate gene-by-environment interaction research (cGxl) …

Abstract Early‐life stress (ELS), such as childhood abuse and neglect is a well‐established
risk factor for the development of psychiatric and medical conditions. In the present chapter …

Studies support a link between adolescent romantic involvement and depression.
Adolescent romantic relationships may increase depression risk by introducing chronic …

From the beginning of the quest to comprehend the forces of human development (ie, their
typology and etiology), there was a notion that these forces had different sources: As none of …

Depression is one of the most prevalent disorders worldwide, with high comorbidity with
cardiovascular disease (CVD). Despite significant heritability, robust genetic associations …