Molecular regulation of adipogenesis and potential anti-adipogenic bioactive molecules
D Moseti, A Regassa, WK Kim - International journal of molecular …, 2016 - mdpi.com
Adipogenesis is the process by which precursor stem cells differentiate into lipid laden
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …
adipocytes. Adipogenesis is regulated by a complex and highly orchestrated gene …
Recent progress in genetics, epigenetics and metagenomics unveils the pathophysiology of human obesity
In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …
cause of numerous health complications and increased mortality. Being a complex and …
Transcriptional and epigenetic control of brown and beige adipose cell fate and function
White adipocytes store excess energy in the form of triglycerides, whereas brown and beige
adipocytes dissipate energy in the form of heat. This thermogenic function relies on the …
adipocytes dissipate energy in the form of heat. This thermogenic function relies on the …
[HTML][HTML] PPARγ as a therapeutic target to rescue mitochondrial function in neurological disease
There is increasing evidence for the involvement of mitochondrial dysfunction and oxidative
stress in the pathogenesis of many of the major neurodegenerative and neuroinflammatory …
stress in the pathogenesis of many of the major neurodegenerative and neuroinflammatory …
Zebrafish embryonic lipidomic analysis reveals that the yolk cell is metabolically active in processing lipid
The role of lipids in providing energy and structural cellular components during vertebrate
development is poorly understood. To elucidate these roles further, we visualized lipid …
development is poorly understood. To elucidate these roles further, we visualized lipid …
Arylfluorosulfates inactivate intracellular lipid binding protein (s) through chemoselective SuFEx reaction with a binding site Tyr residue
Arylfluorosulfates have appeared only rarely in the literature and have not been explored as
probes for covalent conjugation to proteins, possibly because they were assumed to …
probes for covalent conjugation to proteins, possibly because they were assumed to …
Maternal and fetal lipid metabolism under normal and gestational diabetic conditions
E Herrera, G Desoye - Hormone molecular biology and clinical …, 2016 - degruyter.com
Maternal lipids are strong determinants of fetal fat mass. Here we review the overall lipid
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …
metabolism in normal and gestational diabetes mellitus (GDM) pregnancies. During early …
Epigenetic plasticity drives adipogenic and osteogenic differentiation of marrow-derived mesenchymal stem cells
Terminal differentiation of multipotent stem cells is achieved through a coordinated cascade
of activated transcription factors and epigenetic modifications that drive gene transcription …
of activated transcription factors and epigenetic modifications that drive gene transcription …
Bisphenol S-and bisphenol A-induced adipogenesis of murine preadipocytes occurs through direct peroxisome proliferator-activated receptor gamma activation
Methods: Murine 3T3-L1 preadipocytes were used to evaluate and compare the adipogenic
potential of BPS to BPA. Cells were treated with 0.01–50 μ M BPS or 0.01–50 μ M BPA and …
potential of BPS to BPA. Cells were treated with 0.01–50 μ M BPS or 0.01–50 μ M BPA and …
The glucocorticoid receptor: cause of or cure for obesity?
K John, JS Marino, ER Sanchez… - American Journal of …, 2016 - journals.physiology.org
Glucocorticoid hormones (GCs) are important regulators of lipid metabolism, promoting
lipolysis with acute treatment but lipogenesis with chronic exposure. Conventional wisdom …
lipolysis with acute treatment but lipogenesis with chronic exposure. Conventional wisdom …