SARS and MERS: recent insights into emerging coronaviruses

E De Wit, N Van Doremalen, D Falzarano… - Nature reviews …, 2016 - nature.com
Abstract The emergence of Middle East respiratory syndrome coronavirus (MERS-CoV) in
2012 marked the second introduction of a highly pathogenic coronavirus into the human …

A review of treatment modalities for Middle East Respiratory Syndrome

Y Mo, D Fisher - Journal of Antimicrobial Chemotherapy, 2016 - academic.oup.com
The Middle East Respiratory Syndrome coronavirus (MERS-CoV) has been a focus of
international attention since its identification in 2012. Epidemiologically it is characterized by …

[HTML][HTML] Feasibility of using convalescent plasma immunotherapy for MERS-CoV infection, Saudi Arabia

YM Arabi, AH Hajeer, T Luke… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
We explored the feasibility of collecting convalescent plasma for passive immunotherapy of
Middle East respiratory syndrome coronavirus (MERS-CoV) infection by using ELISA to …

IVIG in autoimmune disease—Potential next generation biologics

AW Zuercher, R Spirig, AB Morelli, F Käsermann - Autoimmunity reviews, 2016 - Elsevier
Polyclonal plasma-derived IgG is a mainstay therapeutic of immunodeficiency disorders as
well as of various inflammatory autoimmune diseases. In immunodeficiency the primary …

Non-antibiotic treatments for bacterial diseases in an era of progressive antibiotic resistance

SM Opal - Critical Care, 2016 - Springer
The emergence of multi-drug resistant (MDR) microbial pathogens threatens the very
foundation upon which standard antibacterial chemotherapy is based. We must consider …

Passive transfer of a germline-like neutralizing human monoclonal antibody protects transgenic mice against lethal Middle East respiratory syndrome coronavirus …

AS Agrawal, T Ying, X Tao, T Garron, A Algaissi… - Scientific reports, 2016 - nature.com
Abstract Middle East Respiratory Syndrome coronavirus (MERS-CoV) has repeatedly
caused outbreaks in the Arabian Peninsula. To date, no approved medical countermeasures …

[HTML][HTML] Development of medical countermeasures to Middle East respiratory syndrome coronavirus

TM Uyeki, KJ Erlandson, G Korch… - Emerging infectious …, 2016 - ncbi.nlm.nih.gov
Preclinical development of and research on potential Middle East respiratory syndrome
coronavirus (MERS-CoV) medical countermeasures remain preliminary; advancements are …

[HTML][HTML] An effective DNA vaccine platform for Middle East respiratory syndrome coronavirus

AS Cockrell, RS Baric - Annals of Translational Medicine, 2016 - ncbi.nlm.nih.gov
Middle East respiratory syndrome coronavirus (MERS-CoV) is an ongoing emerging
infectious disease across the Arabian Peninsula, with the majority of cases occurring in …

[HTML][HTML] The search for therapeutic options for Middle East Respiratory Syndrome (MERS)

YM Arabi, HH Balkhy, FG Hayden, DS Hui… - Journal of Infection …, 2016 - ncbi.nlm.nih.gov
More than three years after the first case was described, Middle East Respiratory Syndrome
(MERS) coronavirus continues to cause sporadic cases in the community as well as …

Cattle engineered to produce human antibodies against coronavirus

N Bray - Nature Reviews Drug Discovery, 2016 - nature.com
Passive immunotherapy—for example, using specific antibodies—may represent a good
possible treatment strategy against Middle East respiratory syndrome coronavirus (MERS …