Idiopathic pulmonary fibrosis (IPF) is an incurable complex genetic disorder that is
associated with sequence changes in 7 genes (MUC5B, TERT, TERC, RTEL1, PARN …

Goblet cells within the conjunctival epithelium are specialized cells that secrete mucins onto
the surface of the eye. Recent research has demonstrated new characteristics of the cells …

Chronic obstructive pulmonary disease (COPD) is characterized by chronic airflow limitation.
This generic term encompasses emphysema and chronic bronchitis, two common …

Background IL-13 is a T-helper cell type 2 cytokine that plays an important role in the
pathogenesis of asthma. IL-13 exposure for 14 days transforms cultured normal human …

Asthma is a disease characterized by goblet cell differentiation, mucus hypersecretion,
airway inflammation, and airway hyperresponsiveness. miR-125b was downregulated as …

Cystic fibrosis (CF) is the most common life-shortening autosomal recessive disorder in the
Caucasian population and occurs in many other ethnicities worldwide. The daily treatment …

KIF3A, the gene encoding kinesin family member 3A, is a susceptibility gene locus
associated with asthma; however, mechanisms by which KIF3A might influence the …

Asthma exacerbations are heterogeneous conditions that involve the complex interplay
between environmental exposures and innate and adaptive immune function in genetically …

The genus Enterovirus (EV) was so designated because its members replicate primarily in
the human gastrointestinal (GI) tract. The original taxonomic classification of the EVs …

Smoking during pregnancy increases the risk of developing asthma in childhood. In
addition, smoking during pregnancy seems to be a risk factor for development of the chronic …