Diverse applications of nitrones for the synthesis of heterocyclic compounds

LL Anderson - Asian Journal of Organic Chemistry, 2016 - Wiley Online Library
Although best known for their [3+ 2]‐dipolar cycloaddition reactivity and use in the
preparation of isoxazolines and isoxazolidines, nitrones are versatile reagents that undergo …

β-Ionone and its analogs as promising anticancer agents

M Ansari, S Emami - European journal of medicinal chemistry, 2016 - Elsevier
Abstract β-Ionone is an end-ring analog of β-carotenoids which widely distributed in fruit and
vegetables. Recent studies have demonstrated anti-proliferative, anti-metastatic and …

Water‐Assisted Nitrile Oxide Cycloadditions: Synthesis of Isoxazoles and Stereoselective Syntheses of Isoxazolines and 1, 2, 4‐Oxadiazoles

C Kesornpun, T Aree, C Mahidol… - Angewandte Chemie …, 2016 - Wiley Online Library
Conventional methods generate nitrile oxides from oxime halides in organic solvents under
basic conditions. However, the present work revealed that water‐assisted generation of …

Synthesis of Chiral Tertiary Boronic Esters by Oxime‐Directed Catalytic Asymmetric Hydroboration

VM Shoba, NC Thacker, AJ Bochat… - Angewandte Chemie …, 2016 - Wiley Online Library
Chiral boronic esters are useful intermediates in asymmetric synthesis. We have previously
shown that carbonyl‐directed catalytic asymmetric hydroboration (CAHB) is an efficient …

Apoptosis inducing ability of silver decorated highly reduced graphene oxide nanocomposites in A549 lung cancer

M Khan, M Khan, AH Al-Marri… - International Journal …, 2016 - Taylor & Francis
Recently, graphene and graphene-based materials have been increasingly used for various
biological applications due to their extraordinary physicochemical properties. Here, we …

Synthesis of Diheteroatomic Five‐Membered Heterocyclic Compounds from α, β‐Unsaturated Aldehydes

NA Keiko, NV Vchislo - Asian Journal of Organic Chemistry, 2016 - Wiley Online Library
The recent increase in interest in the chemistry of azoles has been owing to their paramount
importance in several essential fields of research, such as pharmacology, medicine, biology …

Enolate-mediated 1, 3-dipolar cycloaddition reaction of β-functionalized ketones with nitrile oxides: direct access to 3, 4, 5-trisubstituted isoxazoles

X Zhou, X Xu, Z Shi, K Liu, H Gao, W Li - Organic & Biomolecular …, 2016 - pubs.rsc.org
Enolate-mediated 1,3-dipolar cycloaddition reaction of β-functionalized ketones with nitrile
oxides: direct access to 3,4,5-trisubstituted isoxazoles ... - Organic & Biomolecular Chemistry …

Synthesis and biological evaluation of salicylic acid conjugated isoxazoline analogues on immune cell proliferation and angiogenesis

N Puttaswamy, GSP Kumar, M Al-Ghorbani… - European Journal of …, 2016 - Elsevier
Mitogenicity is the ability of the natural or synthetic compounds to induce cell division or
proliferation. A series of salicylic acid derivatives containing isoxazoline moiety (8a-j) were …

Design and synthesis of antimicrobial, anticoagulant, and anticholinesterase hybrid molecules from 4-methylumbelliferone

M Zayane, A Rahmouni, M Daami-Remadi… - Journal of Enzyme …, 2016 - Taylor & Francis
We designed and synthesized new series of diverse triazoles, isoxazoles, isoxazolines, and
aziridines linked 4-methylumbelliferone 1 using intermolecular 1, 3-dipolar cycloaddition …

Isoxazole derivatives of alpha-pinene isomers: Synthesis, crystal structure, spectroscopic characterization (FT-IR/NMR/GC–MS) and DFT studies

S Eryılmaz, M Gül, E Inkaya, M Taş - Journal of Molecular Structure, 2016 - Elsevier
In this paper, the alpha-pinene isoxazole derivatives (3a-bc, 4a-b) were synthesized via 1, 3-
dipolar cycloaddition and characterized with FT-IR, 1 H NMR, 13 C NMR and GC–MS …