Inflammation is a complex biologic response that is essential for eliminating microbial
pathogens and repairing tissue after injury. AKI associates with intrarenal and systemic …

Acute kidney injury (AKI) is a common consequence of systemic illness or injury and it
complicates several forms of major surgery. Two major difficulties have hampered progress …

Acute kidney injury (AKI) is a serious complication, commonly occurring in the critically ill
population, with devastating short-and long-term consequences. Despite standardization of …

Objectives: To examine the performance of the urinary biomarker panel tissue inhibitor of
metalloproteinase-2 and insulin-like growth factor-binding protein 7 in patients with sepsis at …

BACKGROUND Acute kidney injury (AKI) is an important complication in surgical patients.
Existing biomarkers and clinical prediction models underestimate the risk for developing …

Extracorporeal membrane oxygenation (ECMO) is a modified cardiopulmonary bypass
(CPB) circuit capable of providing prolonged cardiorespiratory support. Recent …

Acute kidney injury (AKI) is a syndrome that has progressed a great deal over the last 20
years. The decrease in urine output and the increase in classical renal biomarkers, such as …

The use of novel biomarkers of acute kidney injury (AKI) in clinical trials may help evaluate
treatments for AKI. Here we explore potential applications of biomarkers in simulated clinical …

The RIFLE classification was introduced in 2004 to describe the presence of acute kidney
injury (AKI) and to define its clinical stage, based upon the serum creatinine level and urine …

Accompanied with the broad application of interventional therapy, the incidence of acute
kidney injury (AKI) has been recently increasing in clinical renal medicine. The …