Dysregulation of ubiquitin-proteasome system in neurodegenerative diseases
The ubiquitin-proteasome system (UPS) is one of the major protein degradation pathways,
where abnormal UPS function has been observed in cancer and neurological diseases …
where abnormal UPS function has been observed in cancer and neurological diseases …
Efficient synthesis of longer Aβ peptides via removable backbone modification
C Zuo, S Tang, YY Si, ZA Wang, CL Tian… - Organic & biomolecular …, 2016 - pubs.rsc.org
Longer amyloid-beta (Aβ) peptides (43 to 49 amino acids) play essential roles in the
pathology of Alzheimer's disease (AD). The difficulty in the preparation of longer Aβ peptides …
pathology of Alzheimer's disease (AD). The difficulty in the preparation of longer Aβ peptides …
Experimental Transmission of Alzheimer's Disease Endophenotypes to Murine and Primate Models
C Gary - 2016 - theses.hal.science
Alzheimer's disease (AD) is characterized by the accumulation of misfolded β-amyloid (Aβ)
and Tau proteins. There has been longstanding interest as to whether AD might be …
and Tau proteins. There has been longstanding interest as to whether AD might be …
[图书][B] Synaptopodin is necessary for the enlargement and maintenance of dendritic spines after chemLTP through the regulation of RhoA-GTPase
F Guido - 2016 - search.proquest.com
Dendritic spines are the post-synaptic compartments of the majority of excitatory neurons in
the brain, and these dynamic structures can be modulated by neuronal activity. We have …
the brain, and these dynamic structures can be modulated by neuronal activity. We have …