Impacts and shortcomings of genetic clustering methods for infectious disease outbreaks

AFY Poon - Virus evolution, 2016 - academic.oup.com
For infectious diseases, a genetic cluster is a group of closely related infections that is
usually interpreted as representing a recent outbreak of transmission. Genetic clustering …

Global phylogeography and evolutionary history of Shigella dysenteriae type 1

E Njamkepo, N Fawal, A Tran-Dien, J Hawkey… - Nature …, 2016 - nature.com
Together with plague, smallpox and typhus, epidemics of dysentery have been a major
scourge of human populations for centuries 1. A previous genomic study concluded that …

A high-density SNP panel reveals extensive diversity, frequent recombination and multiple recombination hotspots within the chicken major histocompatibility complex …

JE Fulton, AM McCarron, AR Lund, KN Pinegar… - Genetics Selection …, 2016 - Springer
Background The major histocompatibility complex (MHC) is present within the genomes of
all jawed vertebrates. MHC genes are especially important in regulating immune responses …

Evolutionary dynamics and complicated genetic transmission network patterns of HIV-1 CRF01_AE among MSM in Shanghai, China

X Li, Y Xue, Y Lin, J Gai, L Zhang, H Cheng, Z Ning… - Scientific reports, 2016 - nature.com
To explore the evolutionary dynamics and molecular transmission patterns of HIV-1
CRF01_AE in depth among men who have sex with men (MSM) in Shanghai, we …

[HTML][HTML] MHC variability in heritage breeds of chickens

JE Fulton, AR Lund, AM McCarron, KN Pinegar… - Poultry Science, 2016 - Elsevier
ABSTRACT The chicken Major Histocompatibility Complex (MHC) is very strongly
associated with disease resistance and thus is a very important region of the chicken …

Assessment of overlap of phylogenetic transmission clusters and communities in simple sexual contact networks: applications to HIV-1

L Villandre, DA Stephens, A Labbe, HF Günthard… - PloS one, 2016 - journals.plos.org
Background Transmission patterns of sexually-transmitted infections (STIs) could relate to
the structure of the underlying sexual contact network, whose features are therefore of …

Deep sequencing increases hepatitis C virus phylogenetic cluster detection compared to Sanger sequencing

V Montoya, A Olmstead, P Tang, D Cook… - Infection, Genetics and …, 2016 - Elsevier
Effective surveillance and treatment strategies are required to control the hepatitis C virus
(HCV) epidemic. Phylogenetic analyses are powerful tools for reconstructing the …

[PDF][PDF] Comparing Three HIV-1 Subtyping Tools and a Novel Phylogenetic-Based Method

W Switzer, N Saduvala, T Zhang… - … The Conference on …, 2016 - croiconference.org
Methods▪ We determined subtypes for 69,094 pol sequences> 500-bp in length reported to
the US National HIV Surveillance System between 2001-2014 using three automated tools …

[引用][C] Big data approach for correlating gut microbiota with epithelial methylation pattern Goals: Investigate multi-domain large scale modelling to associate …

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